Bupivacaine Hydrochloride And Epinephrine — Competitive Intelligence Brief

Bupivacaine Hydrochloride And Epinephrine (Bupivacaine Hydrochloride) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Amide local anesthetic.

marketed Amide local anesthetic Nerve sodium channels Small molecule

Target snapshot

Bupivacaine Hydrochloride And Epinephrine (Bupivacaine Hydrochloride) — Pfizer. Bupivacaine blocks nerve impulse generation and conduction by increasing electrical excitation threshold and slowing action potential rise.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine Hydrochloride And Epinephrine TARGET	Bupivacaine Hydrochloride	Pfizer	marketed	Amide local anesthetic	Nerve sodium channels	1972-01-01
Bupivacaine Hydrochloride	Bupivacaine Hydrochloride	Pfizer	marketed	Amide-type local anesthetic	Nerve sodium channels	1972-01-01
Bupivacaine Hydrochloride And Epinephrine	Bupivacaine Hydrochloride	Pfizer	marketed	Amide local anesthetic	Nerve sodium channels	1972-01-01
Bupivacaine Hydrochloride And Epinephrine	Bupivacaine Hydrochloride	Pfizer	marketed	Amide local anesthetic	Nerve sodium channels	1972-01-01
Septocaine	ARTICAINE		marketed	Amide Local Anesthetic	Sodium channel alpha subunits; brain (Types I, II, III)	2000-01-01
Naropin	ROPIVACAINE	Fresenius Kabi	marketed	Amide Local Anesthetic	Sodium channel protein type 5 subunit alpha	1996-01-01
Bupivacaine Hydrochloride And Epinephrine	BUPIVACAINE	Innocoll	marketed	Amide Local Anesthetic	Cytochrome P450 2D6	1972-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

• 2029-05-20 — Bupivacaine Hydrochloride · RE47826 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 10398686 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 11253504 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9592227 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9744163 · US
• 2034-03-13 — Bupivacaine Hydrochloride · 9913909 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 9694079 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 9801945 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10098957 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10213510 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10632199 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10898575 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 10980886 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11083730 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11083797 · US
• 2035-04-20 — Bupivacaine Hydrochloride · 11413350 · US
• 2041-01-12 — Bupivacaine Hydrochloride · 11400019 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11452691 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11179336 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11278494 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11304904 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11311486 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11357727 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11426348 · US
• 2041-01-22 — Bupivacaine Hydrochloride · 11033495 · US

Sponsor landscape (Amide local anesthetic class)

1. Pfizer · 3 drugs in this class