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Maraviroc (MVC) — Competitive Intelligence Brief
marketed
CCR5 antagonist
CCR5 (C-C chemokine receptor type 5)
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
Maraviroc (MVC) (Maraviroc (MVC)) — National Institute of Allergy and Infectious Diseases (NIAID). Maraviroc blocks the CCR5 chemokine receptor on the surface of CD4+ T cells, preventing HIV from entering and infecting these immune cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Maraviroc (MVC) TARGET | Maraviroc (MVC) | National Institute of Allergy and Infectious Diseases (NIAID) | marketed | CCR5 antagonist | CCR5 (C-C chemokine receptor type 5) | |
| Maraviroc, Darunavir/r | Maraviroc, Darunavir/r | Catholic University of the Sacred Heart | marketed | Antiretroviral combination (CCR5 antagonist + protease inhibitor) | CCR5 co-receptor (maraviroc); HIV protease (darunavir) | |
| emtricitabine, darunavir/cobicistat, maraviroc | emtricitabine, darunavir/cobicistat, maraviroc | Giovanni Di Perri | marketed | Antiretroviral combination (NRTI + PI + pharmacokinetic booster + CCR5 antagonist) | HIV reverse transcriptase, HIV protease, CYP3A4, CCR5 co-receptor | |
| Sirolimus + Maraviroc | Sirolimus + Maraviroc | University of Maryland, Baltimore | marketed | mTOR inhibitor + CCR5 antagonist combination | mTOR; CCR5 | |
| Maraviroc + Zidovudine/Lamivudine | Maraviroc + Zidovudine/Lamivudine | ViiV Healthcare | phase 3 | CCR5 antagonist + nucleoside reverse transcriptase inhibitors (NRTIs) | CCR5 co-receptor; HIV reverse transcriptase | |
| Maraviroc (Celsentri) | Maraviroc (Celsentri) | ANRS, Emerging Infectious Diseases | phase 3 | CCR5 antagonist | CCR5 (C-C chemokine receptor type 5) | |
| Celsentri® | Celsentri® | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | phase 3 | CCR5 antagonist | CCR5 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (CCR5 antagonist class)
- ANRS, Emerging Infectious Diseases · 1 drug in this class
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- Theratechnologies · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Maraviroc (MVC) — Competitive Intelligence Brief. https://druglandscape.com/ci/maraviroc-mvc. Accessed 2026-05-16.
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