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LV5FU2 — Competitive Intelligence Brief

LV5FU2 (LV5FU2) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimetabolite chemotherapy combination. Area: Oncology.

phase 3 Antimetabolite chemotherapy combination Thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

LV5FU2 (LV5FU2) — Centre Hospitalier Universitaire de Besancon. LV5FU2 is a combination chemotherapy regimen that inhibits thymidylate synthase and DNA synthesis to kill rapidly dividing cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
LV5FU2 TARGET LV5FU2 Centre Hospitalier Universitaire de Besancon phase 3 Antimetabolite chemotherapy combination Thymidylate synthase
Xeloda capecitabine Cheplapharm marketed Nucleoside Metabolic Inhibitor [EPC] Thymidylate synthase 1998-01-01
Fudr FLOXURIDINE marketed Antimetabolite [EPC] Thymidylate synthase 1970-01-01
Folic Acid FOLIC ACID Pfizer marketed Vitamin C [EPC] Thymidylate synthase 1946-01-01
S-1 S-1 TTY Biopharm marketed Antimetabolite; fluoropyrimidine combination Thymidylate synthase
FLOX FLOX Hospira marketed Thymidylate synthase, Thymidylate synthase
Anlotinib plus Pemetrexed Anlotinib plus Pemetrexed Henan Provincial People's Hospital marketed Multi-target tyrosine kinase inhibitor plus antifolate antimetabolite VEGFR, FGFR, RET, c-Kit (anlotinib); thymidylate synthase, DHFR, GARFT (pemetrexed)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimetabolite chemotherapy combination class)

  1. Asan Medical Center · 1 drug in this class
  2. Centre Hospitalier Universitaire de Besancon · 1 drug in this class
  3. National Health Research Institutes, Taiwan · 1 drug in this class
  4. Odense University Hospital · 1 drug in this class
  5. Pfizer · 1 drug in this class
  6. Shanghai Pulmonary Hospital, Shanghai, China · 1 drug in this class
  7. Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). LV5FU2 — Competitive Intelligence Brief. https://druglandscape.com/ci/lv5fu2. Accessed 2026-05-15.

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