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Luspatercept Injection [Reblozyl] — Competitive Intelligence Brief
phase 2
Erythroid maturation agent
TGF-β superfamily ligands (GDF11, activin A)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Luspatercept Injection [Reblozyl] (Luspatercept Injection [Reblozyl]) — Groupe Francophone des Myelodysplasies. Luspatercept is a recombinant fusion protein that acts as a ligand trap for members of the TGF-β superfamily, modulating Smad2/3 signaling to enhance erythroid maturation.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Luspatercept Injection [Reblozyl] TARGET | Luspatercept Injection [Reblozyl] | Groupe Francophone des Myelodysplasies | phase 2 | Erythroid maturation agent | TGF-β superfamily ligands (GDF11, activin A) | |
| Reblozyl | LUSPATERCEPT | Celgene Corp | marketed | Erythroid Maturation Agent [EPC] | Growth/differentiation factor 11 | 2019-01-01 |
| REBLOZYL | LUSPATERCEPT-AAMT | CELGENE CORP | marketed | Erythroid Maturation Agent [EPC] | Growth/differentiation factor 11, Growth/differentiation factor 8 | |
| Luspatercept Injectable Product | Luspatercept Injectable Product | Sun Yat-sen University | marketed | Erythroid maturation agent | Activin A; TGF-β superfamily ligands |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Erythroid maturation agent class)
- Groupe Francophone des Myelodysplasies · 1 drug in this class
- Sun Yat-sen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Luspatercept Injection [Reblozyl] — Competitive Intelligence Brief. https://druglandscape.com/ci/luspatercept-injection-reblozyl. Accessed 2026-05-16.
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