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Low dose pilocarpine — Competitive Intelligence Brief

Low dose pilocarpine (Low dose pilocarpine) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Muscarinic receptor agonist. Area: Ophthalmology.

phase 3 Muscarinic receptor agonist Muscarinic acetylcholine receptors (M3, M4) Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Low dose pilocarpine (Low dose pilocarpine) — Ocuphire Pharma, Inc.. Low-dose pilocarpine is a muscarinic acetylcholine receptor agonist that stimulates parasympathetic activity to increase aqueous humor outflow and reduce intraocular pressure.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Low dose pilocarpine TARGET Low dose pilocarpine Ocuphire Pharma, Inc. phase 3 Muscarinic receptor agonist Muscarinic acetylcholine receptors (M3, M4)
Pilocarpine Ophthalmic Solution Pilocarpine Ophthalmic Solution Maastricht University Medical Center marketed Muscarinic receptor agonist Muscarinic acetylcholine receptor (M3)
Pilocarpine HCl Pilocarpine HCl Allergan phase 3 Muscarinic receptor agonist Muscarinic M3 receptor
Xanomeline Enteric Capsule Xanomeline Enteric Capsule Bristol-Myers Squibb phase 3 muscarinic receptor agonist M1, M4
Aceclidine ophthalmic solution Aceclidine ophthalmic solution LENZ Therapeutics, Inc phase 3 Muscarinic receptor agonist Muscarinic acetylcholine receptors (M1, M3)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Muscarinic receptor agonist class)

  1. Allergan · 1 drug in this class
  2. LENZ Therapeutics, Inc · 1 drug in this class
  3. Maastricht University Medical Center · 1 drug in this class
  4. Ocuphire Pharma, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Low dose pilocarpine — Competitive Intelligence Brief. https://druglandscape.com/ci/low-dose-pilocarpine. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing