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Low Dose Clomiphencitrat — Competitive Intelligence Brief

Low Dose Clomiphencitrat (Low Dose Clomiphencitrat) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Selective estrogen receptor modulator (SERM). Area: Endocrinology.

marketed Selective estrogen receptor modulator (SERM) Estrogen receptor (ER-α and ER-β) Endocrinology Small molecule Live · refreshed every 30 min

Target snapshot

Low Dose Clomiphencitrat (Low Dose Clomiphencitrat) — University Hospital, Basel, Switzerland. Low-dose clomiphene citrate acts as a selective estrogen receptor modulator (SERM) that blocks negative feedback on the hypothalamic-pituitary-gonadal axis, stimulating endogenous testosterone production in men.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Low Dose Clomiphencitrat TARGET Low Dose Clomiphencitrat University Hospital, Basel, Switzerland marketed Selective estrogen receptor modulator (SERM) Estrogen receptor (ER-α and ER-β)
Toremifene; Anastrozole Toremifene; Anastrozole Peking Union Medical College Hospital marketed Selective estrogen receptor modulator (SERM) + aromatase inhibitor (AI) Estrogen receptor (ER); aromatase (CYP19A1)
tamoxifen citrate (Tamoxifen) tamoxifen citrate (Tamoxifen) H. Lee Moffitt Cancer Center and Research Institute marketed Selective estrogen receptor modulator (SERM) Estrogen receptor alpha (ERα)
raloxifene HCI and alendronate Na raloxifene HCI and alendronate Na Eli Lilly and Company marketed Selective estrogen receptor modulator (SERM) + bisphosphonate combination Estrogen receptor (raloxifene); osteoclast farnesyl pyrophosphate synthase (alendronate)
Tamoxifen (open label) Tamoxifen (open label) Oregon Health and Science University marketed Selective estrogen receptor modulator (SERM) Estrogen receptor alpha (ERα)
fenofibrate and tibolone fenofibrate and tibolone Keogh Institute for Medical Research marketed Fibrate + Selective Estrogen Receptor Modulator (SERM) PPAR-α (fenofibrate); Estrogen receptor, progesterone receptor, androgen receptor (tibolone)
Metformin + Clomiphene Metformin + Clomiphene University of Auckland, New Zealand marketed Combination therapy: biguanide + selective estrogen receptor modulator (SERM) Metformin: AMP-activated protein kinase (AMPK); Clomiphene: estrogen receptor (ER)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Selective estrogen receptor modulator (SERM) class)

  1. University Hospital, Basel, Switzerland · 2 drugs in this class
  2. AstraZeneca · 2 drugs in this class
  3. Estetra · 1 drug in this class
  4. Fundació Privada Eugin · 1 drug in this class
  5. H. Lee Moffitt Cancer Center and Research Institute · 1 drug in this class
  6. National Taiwan University Hospital · 1 drug in this class
  7. Oregon Health and Science University · 1 drug in this class
  8. Samsung Medical Center · 1 drug in this class
  9. Shandong Suncadia Medicine Co., Ltd. · 1 drug in this class
  10. Sheba Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Low Dose Clomiphencitrat — Competitive Intelligence Brief. https://druglandscape.com/ci/low-dose-clomiphencitrat. Accessed 2026-05-17.

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