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low dose capecitabine — Competitive Intelligence Brief

low dose capecitabine (low dose capecitabine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimetabolite. Area: Oncology.

phase 3 Antimetabolite Thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

low dose capecitabine (low dose capecitabine) — Lund University Hospital. Capecitabine is a prodrug that is converted into 5-fluorouracil, which inhibits thymidylate synthase and disrupts DNA synthesis in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
low dose capecitabine TARGET low dose capecitabine Lund University Hospital phase 3 Antimetabolite Thymidylate synthase
Xeloda capecitabine Cheplapharm marketed Nucleoside Metabolic Inhibitor [EPC] Thymidylate synthase 1998-01-01
Fudr FLOXURIDINE marketed Antimetabolite [EPC] Thymidylate synthase 1970-01-01
Folic Acid FOLIC ACID Pfizer marketed Vitamin C [EPC] Thymidylate synthase 1946-01-01
Erlotinib, Pemetrexed Erlotinib, Pemetrexed Hunan Province Tumor Hospital marketed EGFR tyrosine kinase inhibitor + antifolate antimetabolite EGFR; thymidylate synthase and folate-dependent enzymes
Unitrim BRODIMOPRIM marketed brodimoprim Bifunctional dihydrofolate reductase-thymidylate synthase, Dihydrofolate reductase
Irinotecan, 5FU, leucovorin Irinotecan, 5FU, leucovorin Asan Medical Center marketed Chemotherapy combination (topoisomerase I inhibitor + antimetabolite) Topoisomerase I; thymidylate synthase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimetabolite class)

  1. Grupo Espanol Multidisciplinario del Cancer Digestivo · 2 drugs in this class
  2. NRG Oncology · 2 drugs in this class
  3. Bristol-Myers Squibb · 1 drug in this class
  4. EMD Serono Research & Development Institute, Inc. · 1 drug in this class
  5. GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
  6. Hoffmann-La Roche · 1 drug in this class
  7. Centre Oscar Lambret · 1 drug in this class
  8. Iwate Medical University · 1 drug in this class
  9. Janssen Research & Development, LLC · 1 drug in this class
  10. Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · 1 drug in this class

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Cite this brief

Drug Landscape (2026). low dose capecitabine — Competitive Intelligence Brief. https://druglandscape.com/ci/low-dose-capecitabine. Accessed 2026-05-16.

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