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Loperamide hydrochloride + simethicone chewable tablet — Competitive Intelligence Brief
phase 3
Antidiarrheal and antifoaming agent
μ-opioid receptors, gas bubbles
Gastroenterology
Small molecule
Live · refreshed every 30 min
Target snapshot
Loperamide hydrochloride + simethicone chewable tablet (Loperamide hydrochloride + simethicone chewable tablet) — Xian-Janssen Pharmaceutical Ltd.. Loperamide hydrochloride acts on opioid receptors in the gut to slow down intestinal motility, while simethicone reduces surface tension in gas bubbles to facilitate their elimination.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Loperamide hydrochloride + simethicone chewable tablet TARGET | Loperamide hydrochloride + simethicone chewable tablet | Xian-Janssen Pharmaceutical Ltd. | phase 3 | Antidiarrheal and antifoaming agent | μ-opioid receptors, gas bubbles |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
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Sponsor landscape (Antidiarrheal and antifoaming agent class)
- Xian-Janssen Pharmaceutical Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Loperamide hydrochloride + simethicone chewable tablet — Competitive Intelligence Brief. https://druglandscape.com/ci/loperamide-hydrochloride-simethicone-chewable-tablet. Accessed 2026-05-17.
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