Who are LoDAC (Low Dose Cytarabine)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): HIDAC (high dose cytarabine), Cytarabine (Ara-C), Pifeltro, BICTEGRAVIR SODIUM, Biktarvy, Lonsurf.

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Last reviewed 2026-05-17 · How we verify

LoDAC (Low Dose Cytarabine) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

LoDAC (Low Dose Cytarabine) (LoDAC (Low Dose Cytarabine)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Nucleoside analog; antimetabolite. Area: Oncology.

phase 3 Nucleoside analog; antimetabolite DNA polymerase; thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

LoDAC (Low Dose Cytarabine) (LoDAC (Low Dose Cytarabine)) — Astellas Pharma Global Development, Inc.. Low-dose cytarabine is a nucleoside analog that inhibits DNA synthesis by incorporating into DNA and blocking cell division, primarily affecting rapidly dividing hematopoietic cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
LoDAC (Low Dose Cytarabine) TARGET	LoDAC (Low Dose Cytarabine)	Astellas Pharma Global Development, Inc.	phase 3	Nucleoside analog; antimetabolite	DNA polymerase; thymidylate synthase
HIDAC (high dose cytarabine)	HIDAC (high dose cytarabine)	Pfizer	phase 3	Nucleoside analog; antimetabolite	DNA polymerase; thymidylate synthase
Cytarabine (Ara-C)	Cytarabine (Ara-C)	Kura Oncology, Inc.	phase 3	Nucleoside analog; antimetabolite	DNA polymerase; thymidylate synthase
Pifeltro	DORAVIRINE	Merck & Co.	marketed	Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]		2018-01-01
BICTEGRAVIR SODIUM	BICTEGRAVIR SODIUM		marketed	Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]		2018-01-01
Biktarvy	BICTEGRAVIR	Gilead Sciences	marketed	Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor [EPC]		2018-01-01
Lonsurf	TIPIRACIL	Taiho Oncology Inc	marketed	Nucleoside Analog Antiviral [EPC]	Thymidine phosphorylase	2015-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-09-22 — Lonsurf · RE46284 · US
2032-08-15 — Biktarvy · 8754065 · US
2032-08-15 — Biktarvy · 9296769 · US
2033-02-15 — Biktarvy · 8754065*PED · US
2033-02-15 — Biktarvy · 9296769*PED · US
2033-12-19 — Biktarvy · 9216996 · US
2033-12-19 — Biktarvy · 9732092 · US
2034-06-17 — Lonsurf · 10457666 · US
2034-06-17 — Lonsurf · 9527833 · US
2034-09-05 — Lonsurf · 9943537 · US
2035-06-19 — Biktarvy · 9708342 · US
2035-06-19 — Biktarvy · 10385067 · US
2036-11-08 — Biktarvy · 10548846 · US
2037-02-03 — Lonsurf · 10960004 · US
2037-02-03 — Lonsurf · 10456399 · US

Sponsor landscape (Nucleoside analog; antimetabolite class)

Assistance Publique - Hôpitaux de Paris · 1 drug in this class
Astellas Pharma Global Development, Inc. · 1 drug in this class
AstraZeneca · 1 drug in this class
Celgene · 1 drug in this class
Centre Hospitalier Universitaire Dijon · 1 drug in this class
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 1 drug in this class
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. · 1 drug in this class
Eisai Inc. · 1 drug in this class
Gruppo Italiano Malattie EMatologiche dell'Adulto · 1 drug in this class
Jiangsu Simcere Pharmaceutical Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). LoDAC (Low Dose Cytarabine) — Competitive Intelligence Brief. https://druglandscape.com/ci/lodac-low-dose-cytarabine. Accessed 2026-05-17.

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