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Last reviewed 2026-05-14 · How we verify

Lithium / Fluoxetine — Competitive Intelligence Brief

Lithium / Fluoxetine (Lithium / Fluoxetine) competitive landscape: 1 comparator, recent regulatory actions, upcoming PDUFA, patent timeline. Class: SSRI + mood stabilizer combination. Area: Psychiatry / Neurology.

marketed SSRI + mood stabilizer combination Serotonin transporter (SERT); inositol monophosphatase Psychiatry / Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Lithium / Fluoxetine (Lithium / Fluoxetine) — University of Pennsylvania. Lithium enhances serotonergic neurotransmission by inhibiting inositol monophosphatase while fluoxetine blocks serotonin reuptake, together augmenting central serotonergic activity for mood stabilization and antidepressant effects.

Comparator set (1 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Lithium / Fluoxetine TARGET	Lithium / Fluoxetine	University of Pennsylvania	marketed	SSRI + mood stabilizer combination	Serotonin transporter (SERT); inositol monophosphatase
Paroxetine+Lithium	Paroxetine+Lithium	Ministry of Health & Welfare, Korea	marketed	SSRI + mood stabilizer combination	Serotonin transporter (SERT); inositol monophosphatase; protein kinase C

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (SSRI + mood stabilizer combination class)

Ministry of Health & Welfare, Korea · 1 drug in this class
University of Pennsylvania · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Lithium / Fluoxetine — Competitive Intelligence Brief. https://druglandscape.com/ci/lithium-fluoxetine. Accessed 2026-05-14.

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