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Liposomal Amphotericin B with Miltefosine — Competitive Intelligence Brief
phase 3
Antifungal/antiparasitic combination
Fungal ergosterol; phosphatidylcholine synthesis pathway
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Liposomal Amphotericin B with Miltefosine (Liposomal Amphotericin B with Miltefosine) — Banaras Hindu University. Liposomal amphotericin B disrupts fungal cell membranes while miltefosine inhibits phosphatidylcholine synthesis, together providing enhanced antifungal and antiparasitic activity.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Liposomal Amphotericin B with Miltefosine TARGET | Liposomal Amphotericin B with Miltefosine | Banaras Hindu University | phase 3 | Antifungal/antiparasitic combination | Fungal ergosterol; phosphatidylcholine synthesis pathway | |
| Ambisome + Miltefosine | Ambisome + Miltefosine | Drugs for Neglected Diseases | phase 3 | Antifungal/antiparasitic combination | Ergosterol (amphotericin B); phosphatidylcholine synthesis pathway (miltefosine) | |
| liposomal amphotericin B + paromomycin | liposomal amphotericin B + paromomycin | Drugs for Neglected Diseases | phase 3 | Antifungal/antiparasitic combination | Ergosterol (amphotericin B); ribosomal protein synthesis (paromomycin) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifungal/antiparasitic combination class)
- Drugs for Neglected Diseases · 2 drugs in this class
- Banaras Hindu University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Liposomal Amphotericin B with Miltefosine — Competitive Intelligence Brief. https://druglandscape.com/ci/liposomal-amphotericin-b-with-miltefosine. Accessed 2026-05-17.
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