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liposomal amphotericin B + miltefosine — Competitive Intelligence Brief
phase 3
Antifungal
Ergosterol, Sphingosine N-acyltransferase
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
liposomal amphotericin B + miltefosine (liposomal amphotericin B + miltefosine) — Drugs for Neglected Diseases. Liposomal amphotericin B targets fungal cell membranes, while miltefosine targets fungal cell membranes and inhibits sphingosine N-acyltransferase.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| liposomal amphotericin B + miltefosine TARGET | liposomal amphotericin B + miltefosine | Drugs for Neglected Diseases | phase 3 | Antifungal | Ergosterol, Sphingosine N-acyltransferase | |
| Vivjoa | OTESECONAZOLE | Mycovia Pharms | marketed | Azole Antifungal [EPC] | Cytochrome P450 3A4 | 2022-01-01 |
| Brexafemme | IBREXAFUNGERP CITRATE | GSK | marketed | Triterpenoid Antifungal | 2021-01-01 | |
| Brexafemme | IBREXAFUNGERP | GSK | marketed | Triterpenoid Antifungal | 2021-01-01 | |
| Cresemba | ISAVUCONAZONIUM | Astellas Pharma | marketed | Azole Antifungal | ATP-binding cassette sub-family G member 2 | 2015-01-01 |
| Jublia | EFINACONAZOLE | Bausch Health | marketed | Azole Antifungal [EPC] | 2014-01-01 | |
| Luzu | LULICONAZOLE | Bausch Health | marketed | Azole Antifungal [EPC] | 2013-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifungal class)
- Cidara Therapeutics Inc. · 1 drug in this class
- Drugs for Neglected Diseases · 1 drug in this class
- Fernanda P Silveira, MD, MS · 1 drug in this class
- LI YAN · 1 drug in this class
- Novartis · 1 drug in this class
- Polichem S.A. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). liposomal amphotericin B + miltefosine — Competitive Intelligence Brief. https://druglandscape.com/ci/liposomal-amphotericin-b-miltefosine. Accessed 2026-05-16.
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