Who are Leuprolide (GnRH agonists)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Triptorelin (GnRH agonists), Triptorelin pamoate（15mg）, GnRH agonist trigger, Zoladex and Casodex, TRIPTORELIN ACETATE, hCG, GnRH agonist/antagonist.

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Last reviewed 2026-06-10 · How we verify

Leuprolide (GnRH agonists) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Leuprolide (GnRH agonists) (Leuprolide (GnRH agonists)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GnRH agonist. Area: Oncology; Endocrinology.

marketed GnRH agonist GnRH receptor (GNRHR) Oncology; Endocrinology Small molecule Live · refreshed every 30 min

Target snapshot

Leuprolide (GnRH agonists) (Leuprolide (GnRH agonists)) — University of Pisa. Leuprolide is a GnRH agonist that initially stimulates, then suppresses gonadotropin release, leading to decreased testosterone and estrogen production.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Leuprolide (GnRH agonists) TARGET	Leuprolide (GnRH agonists)	University of Pisa	marketed	GnRH agonist	GnRH receptor (GNRHR)
Triptorelin (GnRH agonists)	Triptorelin (GnRH agonists)	University of Pisa	marketed	GnRH agonist	GnRH receptor (GNRHR)
Triptorelin pamoate（15mg）	Triptorelin pamoate（15mg）	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	marketed	GnRH agonist	GnRH receptor
GnRH agonist trigger	GnRH agonist trigger	Rambam Health Care Campus	marketed	GnRH agonist	GnRH receptor
Zoladex and Casodex	Zoladex and Casodex	AstraZeneca	marketed	GnRH agonist (Zoladex) and androgen receptor antagonist (Casodex)	GnRH receptor (Zoladex); androgen receptor (Casodex)
TRIPTORELIN ACETATE, hCG	TRIPTORELIN ACETATE, hCG	HaEmek Medical Center, Israel	marketed	GnRH agonist	GnRH receptor
GnRH agonist/antagonist	GnRH agonist/antagonist	Memorial Sloan Kettering Cancer Center	marketed	GnRH agonist/antagonist	GnRH receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (GnRH agonist class)

Takeda · 4 drugs in this class
Abbott · 3 drugs in this class
Ipsen · 3 drugs in this class
Changchun GeneScience Pharmaceutical Co., Ltd. · 3 drugs in this class
University of Pisa · 2 drugs in this class
Chong Qing Reproducive and Genetic Institute · 1 drug in this class
Chesapeake Urology Research Associates · 1 drug in this class
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · 1 drug in this class
Enteris BioPharma Inc. · 1 drug in this class
Colorado Center for Reproductive Medicine · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Leuprolide (GnRH agonists) — Competitive Intelligence Brief. https://druglandscape.com/ci/leuprolide-gnrh-agonists. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing