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Leukotriene Receptor Antagonist — Competitive Intelligence Brief
phase 3
Leukotriene receptor antagonist
Cysteinyl leukotriene receptors (CysLT1, CysLT2)
Respiratory / Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Leukotriene Receptor Antagonist (Leukotriene Receptor Antagonist) — King Abdullah International Medical Research Center. Leukotriene receptor antagonists block cysteinyl leukotriene receptors on airway and immune cells, reducing inflammatory mediator signaling.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Leukotriene Receptor Antagonist TARGET | Leukotriene Receptor Antagonist | King Abdullah International Medical Research Center | phase 3 | Leukotriene receptor antagonist | Cysteinyl leukotriene receptors (CysLT1, CysLT2) | |
| Singulair | montelukast | Merck & Co. | marketed | Leukotriene receptor antagonist (LTRA) | Cytochrome P450 2C8, Adenosine receptor A3, Cysteinyl leukotriene receptor 2 | 1998-02-20 |
| Accolate | ZAFIRLUKAST | Strides Pharma Intl | marketed | Leukotriene Receptor Antagonist [EPC] | Cysteinyl leukotriene receptor 1 | 1996-01-01 |
| Montelukast (Low FeNO group) | Montelukast (Low FeNO group) | Hull University Teaching Hospitals NHS Trust | marketed | Leukotriene receptor antagonist | CysLT1 (cysteinyl leukotriene receptor type 1) | |
| Montelukast,mometazon froat | Montelukast,mometazon froat | Istanbul Training and Research Hospital | marketed | Leukotriene receptor antagonist + inhaled corticosteroid combination | Cysteinyl leukotriene receptor 1 (CysLT1) and glucocorticoid receptor | |
| Montelukast placebo granüle | Montelukast placebo granüle | Kecioren Education and Training Hospital | marketed | Leukotriene receptor antagonist | CysLT1 receptor | |
| ICS/LABA and Montelukast | ICS/LABA and Montelukast | The First Affiliated Hospital of Guangzhou Medical University | marketed | ICS/LABA combination with leukotriene receptor antagonist | Glucocorticoid receptor, beta-2 adrenergic receptor, cysteinyl leukotriene receptor (CysLT1) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Leukotriene receptor antagonist class)
- Organon and Co · 2 drugs in this class
- Hull University Teaching Hospitals NHS Trust · 2 drugs in this class
- ALK-Abelló A/S · 1 drug in this class
- King Abdullah International Medical Research Center · 1 drug in this class
- SamA Pharmaceutical Co., Ltd · 1 drug in this class
- Kecioren Education and Training Hospital · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Leukotriene Receptor Antagonist — Competitive Intelligence Brief. https://druglandscape.com/ci/leukotriene-receptor-antagonist. Accessed 2026-05-18.
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