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Letrozol step up dose — Competitive Intelligence Brief
phase 3
Aromatase inhibitor
Aromatase (CYP19A1)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Letrozol step up dose (Letrozol step up dose) — Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Letrozole is an aromatase inhibitor that blocks the conversion of androgens to estrogen, reducing circulating estrogen levels in postmenopausal women.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Letrozol step up dose TARGET | Letrozol step up dose | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | phase 3 | Aromatase inhibitor | Aromatase (CYP19A1) | |
| Kisqali | ribociclib | Novartis | marketed | CDK4/6 inhibitor; aromatase inhibitor | Cyclin-dependent kinase (CDK) 4 and 6; aromatase enzyme | 2017-01-01 |
| Aromasin | exemestane | Pfizer | marketed | Aromatase Inhibitor [EPC] | Aromatase | 1999-01-01 |
| Femara | letrozole | Novartis AG | marketed | Aromatase Inhibitor [EPC] | aromatase enzyme | 1997-07-25 |
| LETROZOLE | LETROZOLE | marketed | Aromatase Inhibitor [EPC] | 1997-01-01 | ||
| Arimidex | anastrozole | AstraZeneca | marketed | Aromatase inhibitor | Aromatase enzyme | 1995-12-27 |
| ANASTROZOLE | ANASTROZOLE | marketed | Aromatase Inhibitor [EPC] | aromatase | 1995-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Aromatase inhibitor class)
- AstraZeneca · 4 drugs in this class
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · 2 drugs in this class
- Eastern Virginia Medical School · 1 drug in this class
- Genor Biopharma Co., Ltd. · 1 drug in this class
- Gynaecologisch Oncologisch Centrum Zuid · 1 drug in this class
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy · 1 drug in this class
- IVI Madrid · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Lumara Health, Inc. · 1 drug in this class
- Pfizer · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Letrozol step up dose — Competitive Intelligence Brief. https://druglandscape.com/ci/letrozol-step-up-dose. Accessed 2026-06-10.
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