Last reviewed · How we verify
lenalidomide, bortezomib and dexamethasone — Competitive Intelligence Brief
phase 3
Combination therapy: immunomodulatory agent, proteasome inhibitor, and corticosteroid
Multiple targets: cereblon (lenalidomide), 20S proteasome (bortezomib), glucocorticoid receptor (dexamethasone)
Oncology
Small molecule
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Target snapshot
lenalidomide, bortezomib and dexamethasone (lenalidomide, bortezomib and dexamethasone) — National Heart, Lung, and Blood Institute (NHLBI). This three-drug combination works by enhancing immune cell activity (lenalidomide), inhibiting proteasome function to trigger cancer cell death (bortezomib), and suppressing inflammation (dexamethasone) to treat multiple myeloma.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| lenalidomide, bortezomib and dexamethasone TARGET | lenalidomide, bortezomib and dexamethasone | National Heart, Lung, and Blood Institute (NHLBI) | phase 3 | Combination therapy: immunomodulatory agent, proteasome inhibitor, and corticosteroid | Multiple targets: cereblon (lenalidomide), 20S proteasome (bortezomib), glucocorticoid receptor (dexamethasone) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination therapy: immunomodulatory agent, proteasome inhibitor, and corticosteroid class)
- National Heart, Lung, and Blood Institute (NHLBI) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). lenalidomide, bortezomib and dexamethasone — Competitive Intelligence Brief. https://druglandscape.com/ci/lenalidomide-bortezomib-and-dexamethasone. Accessed 2026-05-16.
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