Last reviewed · How we verify
Dayvigo — Competitive Intelligence Brief
marketed
Orexin Receptor Antagonist [EPC]
Orexin receptor type 2
Neuroscience
Small molecule
Live · refreshed every 30 min
Target snapshot
Dayvigo (LEMBOREXANT) — Eisai. Dayvigo blocks the action of orexin, a neurotransmitter that helps regulate sleep-wake cycles.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Dayvigo TARGET | LEMBOREXANT | Eisai | marketed | Orexin Receptor Antagonist [EPC] | Orexin receptor type 2 | 2019-01-01 |
| Quviviq | DARIDOREXANT | Idorsia | marketed | Orexin Receptor Antagonist [EPC] | Orexin receptor type 1 | 2022-01-01 |
| Suvorexant (Belsomra) | Suvorexant (Belsomra) | Massachusetts General Hospital | marketed | Orexin receptor antagonist | Orexin receptor 1 (OX1R) and Orexin receptor 2 (OX2R) | |
| Suvorexant High Dose (HD) | Suvorexant High Dose (HD) | Merck Sharp & Dohme LLC | phase 3 | Orexin receptor antagonist | OX1R and OX2R (orexin receptors 1 and 2) | |
| Dose-matched Placebo to Suvorexant | Dose-matched Placebo to Suvorexant | Merck Sharp & Dohme LLC | phase 3 | Orexin receptor antagonist | OX1R and OX2R (orexin receptors) | |
| Suvorexant Low Dose (LD) | Suvorexant Low Dose (LD) | Merck Sharp & Dohme LLC | phase 3 | Orexin receptor antagonist | OX1R and OX2R (orexin receptors 1 and 2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Orexin Receptor Antagonist [EPC] class)
- Eisai · 1 drug in this class
- Idorsia · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Dayvigo — Competitive Intelligence Brief. https://druglandscape.com/ci/lemborexant. Accessed 2026-05-13.
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