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Leflunomide 10 milligram (MG) — Competitive Intelligence Brief

Leflunomide 10 milligram (MG) (Leflunomide 10 milligram (MG)) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: DHODH inhibitor; disease-modifying antirheumatic drug (DMARD). Area: Immunology; Rheumatology.

marketed DHODH inhibitor; disease-modifying antirheumatic drug (DMARD) Dihydroorotate dehydrogenase (DHODH) Immunology; Rheumatology Small molecule Live · refreshed every 30 min

Target snapshot

Leflunomide 10 milligram (MG) (Leflunomide 10 milligram (MG)) — P. Verschueren. Leflunomide inhibits dihydroorotate dehydrogenase, an enzyme required for pyrimidine synthesis, thereby suppressing T-cell and B-cell proliferation.

Comparator set (2 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Leflunomide 10 milligram (MG) TARGET Leflunomide 10 milligram (MG) P. Verschueren marketed DHODH inhibitor; disease-modifying antirheumatic drug (DMARD) Dihydroorotate dehydrogenase (DHODH)
Leflunomide(LEF) Leflunomide(LEF) Nanjing Children's Hospital marketed Immunosuppressant; DHODH inhibitor Dihydroorotate dehydrogenase (DHODH)
IMU-838 tablets IMU-838 tablets Immunic AG phase 3 DHODH inhibitor Dihydroorotate dehydrogenase (DHODH)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (DHODH inhibitor; disease-modifying antirheumatic drug (DMARD) class)

  1. P. Verschueren · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Leflunomide 10 milligram (MG) — Competitive Intelligence Brief. https://druglandscape.com/ci/leflunomide-10-milligram-mg. Accessed 2026-05-16.

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