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Leflunomide 10 milligram (MG) — Competitive Intelligence Brief
marketed
DHODH inhibitor; disease-modifying antirheumatic drug (DMARD)
Dihydroorotate dehydrogenase (DHODH)
Immunology; Rheumatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Leflunomide 10 milligram (MG) (Leflunomide 10 milligram (MG)) — P. Verschueren. Leflunomide inhibits dihydroorotate dehydrogenase, an enzyme required for pyrimidine synthesis, thereby suppressing T-cell and B-cell proliferation.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Leflunomide 10 milligram (MG) TARGET | Leflunomide 10 milligram (MG) | P. Verschueren | marketed | DHODH inhibitor; disease-modifying antirheumatic drug (DMARD) | Dihydroorotate dehydrogenase (DHODH) | |
| Leflunomide(LEF) | Leflunomide(LEF) | Nanjing Children's Hospital | marketed | Immunosuppressant; DHODH inhibitor | Dihydroorotate dehydrogenase (DHODH) | |
| IMU-838 tablets | IMU-838 tablets | Immunic AG | phase 3 | DHODH inhibitor | Dihydroorotate dehydrogenase (DHODH) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (DHODH inhibitor; disease-modifying antirheumatic drug (DMARD) class)
- P. Verschueren · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Leflunomide 10 milligram (MG) — Competitive Intelligence Brief. https://druglandscape.com/ci/leflunomide-10-milligram-mg. Accessed 2026-05-16.
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