Last reviewed · How we verify
Lebrikizumab Pen — Competitive Intelligence Brief
phase 3
IL-4 receptor antagonist; monoclonal antibody
IL-4Rα (Interleukin-4 receptor alpha)
Immunology; Respiratory/Allergy
Small molecule
Live · refreshed every 30 min
Target snapshot
Lebrikizumab Pen (Lebrikizumab Pen) — Eli Lilly and Company. Lebrikizumab is a monoclonal antibody that blocks interleukin-4 receptor alpha (IL-4Rα), inhibiting IL-4 and IL-13 signaling to reduce type 2 inflammation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Lebrikizumab Pen TARGET | Lebrikizumab Pen | Eli Lilly and Company | phase 3 | IL-4 receptor antagonist; monoclonal antibody | IL-4Rα (Interleukin-4 receptor alpha) | |
| Dupilumab Prefilled Syringe | Dupilumab Prefilled Syringe | Jonathan A. Bernstein, MD | marketed | Monoclonal antibody; IL-4 receptor antagonist | IL-4 receptor alpha (IL-4Rα) | |
| Dupilumab (SAR231893) | Dupilumab (SAR231893) | Sanofi | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Dupilumab step-down | Dupilumab step-down | Nantes University Hospital | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Dupilumab - Dose Reduction | Dupilumab - Dose Reduction | Johns Hopkins University | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Dupilumab Injectable Product | Dupilumab Injectable Product | University of Virginia | marketed | IL-4 receptor antagonist monoclonal antibody | IL-4 receptor alpha (IL-4Rα) | |
| Placebo matching depemokimab | Placebo matching depemokimab | GlaxoSmithKline | phase 3 | IL-4 receptor antagonist monoclonal antibody | IL-4Rα (Interleukin-4 receptor alpha) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (IL-4 receptor antagonist; monoclonal antibody class)
- Eli Lilly and Company · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Lebrikizumab Pen — Competitive Intelligence Brief. https://druglandscape.com/ci/lebrikizumab-pen. Accessed 2026-05-17.
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