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LDX Treatment — Competitive Intelligence Brief
marketed
Sympathomimetic amine; amphetamine prodrug
Norepinephrine transporter (NET); dopamine transporter (DAT)
Psychiatry / Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
LDX Treatment (LDX Treatment) — NYU Langone Health. LDX (lisdexamfetamine) is a prodrug that is metabolized to d-amphetamine, which increases the release and blocks the reuptake of norepinephrine and dopamine in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| LDX Treatment TARGET | LDX Treatment | NYU Langone Health | marketed | Sympathomimetic amine; amphetamine prodrug | Norepinephrine transporter (NET); dopamine transporter (DAT) | |
| Propadrine | PHENYLPROPANOLAMINE | Alpharma Us Pharms | marketed | Indirectly Acting Sympathomimetic Amines | Sodium-dependent noradrenaline transporter | 2000-01-01 |
| Didrex | BENZPHETAMINE | Pfizer | marketed | Sympathomimetic Amine Anorectic | Alpha-1A adrenergic receptor | 1960-01-01 |
| Tenuate | DIETHYLPROPION | ANI Pharmaceuticals | marketed | Sympathomimetic Amine Anorectic | Sodium-dependent dopamine transporter | 1959-01-01 |
| Aramine | METARAMINOL | marketed | Indirectly Acting Sympathomimetic Amines | Macrophage migration inhibitory factor | 1954-01-01 | |
| Vialin | MEPHENTERMINE | Baxter | marketed | Indirectly Acting Sympathomimetic Amines | Alpha-1A adrenergic receptor | 1951-01-01 |
| Aptensio XR | Aptensio XR | Rhodes Pharmaceuticals, L.P. | marketed | Sympathomimetic amine; CNS stimulant | Dopamine transporter (DAT); Norepinephrine transporter (NET) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Sympathomimetic amine; amphetamine prodrug class)
- NYU Langone Health · 1 drug in this class
- Seattle Children's Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). LDX Treatment — Competitive Intelligence Brief. https://druglandscape.com/ci/ldx-treatment. Accessed 2026-06-10.
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