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LC16m8 — Competitive Intelligence Brief
phase 3
Live attenuated viral vaccine
Orthopoxvirus antigens (smallpox virus, monkeypox virus)
Immunology / Infectious Disease
Biologic
Live · refreshed every 30 min
Target snapshot
LC16m8 (LC16m8) — International Vaccine Institute. LC16m8 is a live attenuated vaccinia virus vaccine designed to provide immunization against smallpox and monkeypox through viral replication and immune stimulation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| LC16m8 TARGET | LC16m8 | International Vaccine Institute | phase 3 | Live attenuated viral vaccine | Orthopoxvirus antigens (smallpox virus, monkeypox virus) | |
| MVA-BN vaccine | MVA-BN vaccine | National Institute of Allergy and Infectious Diseases (NIAID) | marketed | Live attenuated viral vaccine | Monkeypox virus antigens (vaccinia virus-vectored) | |
| Measles-Mumps-Rubella | Measles-Mumps-Rubella | Hospital Clinic of Barcelona | marketed | Live attenuated viral vaccine | ||
| M-M-RTM II | M-M-RTM II | Merck Sharp & Dohme LLC | marketed | Live attenuated viral vaccine | ||
| Measles Mumps and Rubella Vaccine | Measles Mumps and Rubella Vaccine | Sanofi | marketed | Live attenuated viral vaccine | ||
| Measles-Rubella (MR) Vaccine | Measles-Rubella (MR) Vaccine | PT Bio Farma | marketed | Live attenuated viral vaccine | ||
| MMR followed by YF | MMR followed by YF | Alba Maria Ropero | marketed | Live attenuated viral vaccine combination |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Live attenuated viral vaccine class)
- Jean-Pierre Van geertruyden · 2 drugs in this class
- Sanofi Pasteur, a Sanofi Company · 2 drugs in this class
- Centers for Disease Control and Prevention · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Hospital Clinic of Barcelona · 1 drug in this class
- Institute of Medical Biology, Chinese Academy of Medical Sciences · 1 drug in this class
- Institute of Tropical Medicine, Belgium · 1 drug in this class
- International Vaccine Institute · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). LC16m8 — Competitive Intelligence Brief. https://druglandscape.com/ci/lc16m8. Accessed 2026-05-14.
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