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Lasofoxifene in combination with abemaciclib — Competitive Intelligence Brief
phase 3
SERM + CDK4/6 inhibitor combination
Estrogen receptor (ER) + CDK4/6
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Lasofoxifene in combination with abemaciclib (Lasofoxifene in combination with abemaciclib) — Sermonix Pharmaceuticals Inc.. Lasofoxifene is a selective estrogen receptor modulator (SERM) that blocks estrogen signaling, combined with abemaciclib, a CDK4/6 inhibitor that prevents cell cycle progression in hormone receptor-positive breast cancer cells.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Lasofoxifene in combination with abemaciclib TARGET | Lasofoxifene in combination with abemaciclib | Sermonix Pharmaceuticals Inc. | phase 3 | SERM + CDK4/6 inhibitor combination | Estrogen receptor (ER) + CDK4/6 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (SERM + CDK4/6 inhibitor combination class)
- Sermonix Pharmaceuticals Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Lasofoxifene in combination with abemaciclib — Competitive Intelligence Brief. https://druglandscape.com/ci/lasofoxifene-in-combination-with-abemaciclib. Accessed 2026-05-16.
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