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Vitrakvi — Competitive Intelligence Brief

Vitrakvi (LAROTRECTINIB) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Kinase Inhibitor [EPC]. Area: Oncology.

marketed Kinase Inhibitor [EPC] High affinity nerve growth factor receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Vitrakvi (LAROTRECTINIB) — Bayer. Vitrakvi works by blocking the activity of a specific protein called the nerve growth factor receptor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Vitrakvi TARGET LAROTRECTINIB Bayer marketed Kinase Inhibitor [EPC] High affinity nerve growth factor receptor 2018-01-01
Rozlytrek entrectinib Roche marketed High affinity nerve growth factor receptor 2019-01-01
Oxervate CENEGERMIN Dompe farmaceutici s.p.a. marketed Recombinant Human Nerve Growth Factor [EPC] High affinity nerve growth factor receptor 2017-01-01
Oxervate Oxervate Dompé Farmaceutici S.p.A marketed High affinity nerve growth factor receptor, Tumor necrosis factor receptor superfamily member 16
Oxervate Cenegermin-Bkbj Dompe farmaceutici s.p.a. marketed Recombinant Human Nerve Growth Factor [EPC] High affinity nerve growth factor receptor
Itovebi INAVOLISIB Genentech Inc marketed Kinase Inhibitor [EPC] 2025-01-01
Romvimza VIMSELTINIB Deciphera Pharms marketed Kinase Inhibitor [EPC] 2025-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Kinase Inhibitor [EPC] class)

  1. · 12 drugs in this class
  2. Pfizer · 7 drugs in this class
  3. Novartis · 3 drugs in this class
  4. Bayer · 2 drugs in this class
  5. Boehringer Ingelheim · 2 drugs in this class
  6. AstraZeneca · 2 drugs in this class
  7. Beigene Usa Inc · 1 drug in this class
  8. BeiGene · 1 drug in this class
  9. AbbVie · 1 drug in this class
  10. Bristol · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Vitrakvi — Competitive Intelligence Brief. https://druglandscape.com/ci/larotrectinib. Accessed 2026-05-14.

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