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Lévétiracetam — Competitive Intelligence Brief
phase 3
Antiepileptic agent
SV2A (synaptic vesicle protein 2A)
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Lévétiracetam (Lévétiracetam) — Hospices Civils de Lyon. Levetiracetam reduces neuronal excitability by binding to synaptic vesicle protein SV2A, thereby modulating neurotransmitter release and preventing seizure propagation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Lévétiracetam TARGET | Lévétiracetam | Hospices Civils de Lyon | phase 3 | Antiepileptic agent | SV2A (synaptic vesicle protein 2A) | |
| Keppra | levetiracetam | Generic (originally UCB Pharma) | marketed | Antiepileptic agent | Synaptic vesicle protein SV2A | 1999-11-30 |
| Topiramate-Implant | Topiramate-Implant | University of Sao Paulo | marketed | Anticonvulsant / Antiepileptic agent | GABA-A receptor, sodium channels, glutamate receptors | |
| Lacosamide - rapid titration 1 | Lacosamide - rapid titration 1 | Seoul National University Hospital | marketed | Antiepileptic agent (sodium channel modulator) | Voltage-gated sodium channels (slow inactivation enhancer) | |
| LEV | LEV | GlaxoSmithKline | marketed | Antiepileptic agent | SV2A (synaptic vesicle glycoprotein 2A) | |
| Topiramate monotherapy | Topiramate monotherapy | Johnson & Johnson Taiwan Ltd | marketed | Anticonvulsant / Antiepileptic agent | GABA-A receptor; voltage-gated sodium channels | |
| Oral levetiracetam | Oral levetiracetam | Children's Hospital of Fudan University | marketed | Antiepileptic agent | SV2A (synaptic vesicle protein 2A) |
Recent regulatory actions (last 90 days)
- — Keppra · FDA · approved · US · Generic (originally UCB Pharma)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Keppra · 8163306 · Formulation · US
- — Keppra · 8431156 · Formulation · US
- — Keppra · 8470367 · Formulation · US
- — Keppra · 7858122 · Formulation · US
- — Keppra · 8802142 · Formulation · US
- — Keppra · 8802142*PED · Compound · US
- — Keppra · 11160786 · Formulation · US
- — Keppra · 9669009 · Method of Use · US
- — Keppra · 9339489 · Formulation · US
Sponsor landscape (Antiepileptic agent class)
- Children's Hospital of Fudan University · 1 drug in this class
- Generic (originally UCB Pharma) · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- Hospices Civils de Lyon · 1 drug in this class
- Mario Negri Institute for Pharmacological Research · 1 drug in this class
- Richard H. Haas · 1 drug in this class
- ayesha tariq · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Lévétiracetam — Competitive Intelligence Brief. https://druglandscape.com/ci/l-v-tiracetam. Accessed 2026-06-10.
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