L-tryptophan supplementation — Competitive Intelligence Brief

L-tryptophan supplementation (L-tryptophan supplementation) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Amino acid supplement. Area: Psychiatry/Neurology.

phase 3 Amino acid supplement Serotonin synthesis pathway (tryptophan hydroxylase substrate) Psychiatry/Neurology Small molecule

Target snapshot

L-tryptophan supplementation (L-tryptophan supplementation) — University of Colorado, Denver. L-tryptophan supplementation increases the availability of tryptophan, an essential amino acid that serves as a precursor for serotonin and other neurotransmitters.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
L-tryptophan supplementation TARGET	L-tryptophan supplementation	University of Colorado, Denver	phase 3	Amino acid supplement	Serotonin synthesis pathway (tryptophan hydroxylase substrate)
5-Hydroxytryptophan	5-Hydroxytryptophan	Elizabeth Berry-Kravis	marketed	Serotonin precursor / amino acid supplement	Aromatic amino acid decarboxylase (enzyme substrate); indirect serotonin system modulation
L-Tryptophan	L-Tryptophan	McMaster University	marketed	Amino acid supplement
L-Arginine	L-Arginine	The University of Texas at Arlington	marketed	Amino acid supplement	Nitric oxide synthase substrate
Keto Acid	Keto Acid	Peking University First Hospital	marketed	Amino acid supplement / Nutritional agent
keto-amino acids	keto-amino acids	YUAN Wei-jie	marketed	Amino acid supplement / Nutritional therapeutic
L-lysine	L-lysine	University of Zurich	marketed	Amino acid supplement

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Amino acid supplement class)

1. Air Force Military Medical University, China · 1 drug in this class
2. Elijah W. Stommel · 1 drug in this class
3. Hadassah Medical Organization · 1 drug in this class
4. Keith D Lindor, M.D. · 1 drug in this class
5. McMaster University · 1 drug in this class
6. The University of Texas at Arlington · 1 drug in this class
7. Ukrainian Medical Stomatological Academy · 1 drug in this class
8. University Hospital, Strasbourg, France · 1 drug in this class
9. University of Colorado, Denver · 1 drug in this class
10. University of Miami · 1 drug in this class