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L-AmB standard dose — Competitive Intelligence Brief
phase 3
Polyene antifungal
Ergosterol (fungal cell membrane sterol)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
L-AmB standard dose (L-AmB standard dose) — Federal University of Health Science of Porto Alegre. L-AmB (liposomal amphotericin B) binds to ergosterol in fungal cell membranes, creating pores that disrupt membrane integrity and lead to cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| L-AmB standard dose TARGET | L-AmB standard dose | Federal University of Health Science of Porto Alegre | phase 3 | Polyene antifungal | Ergosterol (fungal cell membrane sterol) | |
| Abelcet | AMPHOTERICIN B | Astellas Pharma | marketed | Lipid-based Polyene Antifungal [EPC] | 1964-01-01 | |
| Mycostatin | nystatin | Generic (originally Squibb) | marketed | Polyene Antifungal [EPC] | Ergosterol (fungal cell membrane) | 1954-01-01 |
| Amphotericin B Deoxycholate | Amphotericin B Deoxycholate | Drugs for Neglected Diseases | marketed | Polyene antifungal | Ergosterol | |
| Amphotericin B Liposome | Amphotericin B Liposome | Aurobindo Pharma Ltd | marketed | Lipid-based Polyene Antifungal [EPC] | ||
| Liposomal Amphotericin B | Liposomal Amphotericin B | Taiwan Liposome Company | marketed | Polyene antifungal | Ergosterol | |
| Amphotericin B Lipid emulsion | Amphotericin B Lipid emulsion | Bharat Serums and Vaccines Limited | phase 3 | Polyene antifungal | Ergosterol |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Polyene antifungal class)
- Bharat Serums and Vaccines Limited · 1 drug in this class
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · 1 drug in this class
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. · 1 drug in this class
- Dr. Falk Pharma GmbH · 1 drug in this class
- Drugs for Neglected Diseases · 1 drug in this class
- Federal University of Health Science of Porto Alegre · 1 drug in this class
- Fundacion Nacional de Dermatologia · 1 drug in this class
- Pfizer · 1 drug in this class
- Poitiers University Hospital · 1 drug in this class
- Taiwan Liposome Company · 1 drug in this class
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Cite this brief
Drug Landscape (2026). L-AmB standard dose — Competitive Intelligence Brief. https://druglandscape.com/ci/l-amb-standard-dose. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing