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KSI-101 — Competitive Intelligence Brief
phase 3
Bispecific antibody
VEGF and ANG-2
Ophthalmology
Small molecule
Live · refreshed every 30 min
Target snapshot
KSI-101 (KSI-101) — Kodiak Sciences Inc. KSI-101 is a bispecific antibody that simultaneously targets VEGF and ANG-2 to reduce retinal inflammation and vascular leakage in retinal diseases.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| KSI-101 TARGET | KSI-101 | Kodiak Sciences Inc | phase 3 | Bispecific antibody | VEGF and ANG-2 | |
| Elrexfio | elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrexfio | Elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrantamab | elrantamab | Pfizer | marketed | Bispecific Antibody | BCMA (B-cell maturation antigen) | |
| CHS-1420 | CHS-1420 | Coherus Oncology, Inc. | phase 3 | Bispecific antibody | CD47 and CD40 | |
| M701 | M701 | Wuhan YZY Biopharma Co., Ltd. | phase 3 | Bispecific antibody | ||
| AK112, Gemcitabine, Cisplatin | AK112, Gemcitabine, Cisplatin | Akeso | phase 3 | Bispecific antibody (PD-1/LAG-3 inhibitor) combined with chemotherapy | PD-1 and LAG-3 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bispecific antibody class)
- Shanghai Miracogen Inc. · 3 drugs in this class
- Atom Therapeutics Co., Ltd · 2 drugs in this class
- Pfizer · 2 drugs in this class
- Allergan · 1 drug in this class
- AstraZeneca · 1 drug in this class
- BioNTech SE · 1 drug in this class
- DualityBio Inc. · 1 drug in this class
- Coherus Oncology, Inc. · 1 drug in this class
- Genmab · 1 drug in this class
- Amgen · 1 drug in this class
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Cite this brief
Drug Landscape (2026). KSI-101 — Competitive Intelligence Brief. https://druglandscape.com/ci/ksi-101. Accessed 2026-05-13.
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