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KHK7791 — Competitive Intelligence Brief
phase 3
Factor XIa inhibitor
Factor XIa
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
KHK7791 (KHK7791) — Kyowa Kirin Co., Ltd.. KHK7791 is a Factor XIa inhibitor that reduces thrombin generation by blocking a key coagulation cascade enzyme, thereby reducing thrombotic risk.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| KHK7791 TARGET | KHK7791 | Kyowa Kirin Co., Ltd. | phase 3 | Factor XIa inhibitor | Factor XIa | |
| C1 esterase inhibitor [human] liquid | C1 esterase inhibitor [human] liquid | Shire | phase 3 | Serine protease inhibitor; plasma-derived protein replacement | C1 esterase inhibitor (C1-INH); Factor XIIa, Factor XIa, Kallikrein | |
| KHK7580 | KHK7580 | Kyowa Kirin Co., Ltd. | phase 3 | Factor XIa inhibitor | Factor XIa | |
| KHK4827 | KHK4827 | Kyowa Kirin Co., Ltd. | phase 3 | Factor XIa inhibitor | Factor XIa | |
| BCX7353 capsules | BCX7353 capsules | BioCryst Pharmaceuticals | phase 3 | Plasma kallikrein inhibitor | Plasma kallikrein (Factor XIa) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Factor XIa inhibitor class)
- Kyowa Kirin Co., Ltd. · 3 drugs in this class
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Cite this brief
Drug Landscape (2026). KHK7791 — Competitive Intelligence Brief. https://druglandscape.com/ci/khk7791. Accessed 2026-05-13.
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