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Ketoprofen and Omeprazole — Competitive Intelligence Brief
marketed
NSAID + Proton pump inhibitor combination
COX-1/COX-2 (ketoprofen); H+/K+-ATPase (omeprazole)
Rheumatology / Pain Management / Gastroenterology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ketoprofen and Omeprazole (Ketoprofen and Omeprazole) — Luis Fernando Simoneti. Ketoprofen inhibits prostaglandin synthesis via COX inhibition to reduce inflammation and pain, while omeprazole suppresses gastric acid production to protect against NSAID-induced ulcers.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ketoprofen and Omeprazole TARGET | Ketoprofen and Omeprazole | Luis Fernando Simoneti | marketed | NSAID + Proton pump inhibitor combination | COX-1/COX-2 (ketoprofen); H+/K+-ATPase (omeprazole) | |
| Surgery with Naproxen and Esomeprazole | Surgery with Naproxen and Esomeprazole | Giovana Maria Weckwerth | marketed | NSAID + Proton pump inhibitor combination | COX-1/COX-2 (naproxen); H+/K+-ATPase (esomeprazole) | |
| Diclofenac + Omeprazole | Diclofenac + Omeprazole | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | marketed | NSAID + Proton pump inhibitor combination | COX-1/COX-2 (diclofenac); H+/K+-ATPase (omeprazole) | |
| FDC KETOPROFEN+OMEPRAZOLE | FDC KETOPROFEN+OMEPRAZOLE | Sanofi | phase 3 | NSAID + Proton pump inhibitor combination | COX-1/COX-2 (ketoprofen); H+/K+-ATPase (omeprazole) | |
| Nimesulide + Pantoprazole | Nimesulide + Pantoprazole | EMS | phase 3 | NSAID + Proton pump inhibitor combination | COX-2 enzyme (nimesulide); H+/K+-ATPase (pantoprazole) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NSAID + Proton pump inhibitor combination class)
- EMS · 1 drug in this class
- Giovana Maria Weckwerth · 1 drug in this class
- Luis Fernando Simoneti · 1 drug in this class
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · 1 drug in this class
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ketoprofen and Omeprazole — Competitive Intelligence Brief. https://druglandscape.com/ci/ketoprofen-and-omeprazole. Accessed 2026-05-16.
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