Last reviewed · How we verify
Ketanest®S — Competitive Intelligence Brief
phase 3
NMDA receptor antagonist; dissociative anesthetic
NMDA receptor (N-methyl-D-aspartate receptor)
Anesthesiology
Small molecule
Live · refreshed every 30 min
Target snapshot
Ketanest®S (Ketanest®S) — Chengdu Brilliant Pharmaceutical Co., Ltd.. Ketanest®S is a rapid-acting anesthetic that blocks NMDA receptors in the central nervous system to produce dissociative anesthesia and analgesia.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ketanest®S TARGET | Ketanest®S | Chengdu Brilliant Pharmaceutical Co., Ltd. | phase 3 | NMDA receptor antagonist; dissociative anesthetic | NMDA receptor (N-methyl-D-aspartate receptor) | |
| Memantine (twice daily) | Memantine (twice daily) | H. Lundbeck A/S | marketed | NMDA receptor antagonist | NMDA receptor | |
| Saline + Ketamine | Saline + Ketamine | Ullevaal University Hospital | marketed | NMDA receptor antagonist / Dissociative anesthetic | NMDA receptor (glutamate-gated ion channel) | |
| Naloxone + Ketamine | Naloxone + Ketamine | Ullevaal University Hospital | marketed | Opioid antagonist + NMDA receptor antagonist combination | Opioid receptors (mu, delta, kappa) and NMDA receptor | |
| S (+) Ketamine | S (+) Ketamine | Asker & Baerum Hospital | marketed | NMDA receptor antagonist | NMDA receptor | |
| Midazolam, ketamine | Midazolam, ketamine | Universidade Federal de Goias | marketed | Benzodiazepine + NMDA receptor antagonist combination | GABA-A receptor (midazolam); NMDA glutamate receptor (ketamine) | |
| S-Ketamine 0.5 | S-Ketamine 0.5 | Turku University Hospital | marketed | NMDA receptor antagonist | NMDA receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NMDA receptor antagonist; dissociative anesthetic class)
- Chengdu Brilliant Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ketanest®S — Competitive Intelligence Brief. https://druglandscape.com/ci/ketanests. Accessed 2026-05-15.
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