Ketamine load — Competitive Intelligence Brief

Ketamine load (Ketamine load) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: NMDA receptor antagonist. Area: Anesthesia; Psychiatry (depression).

marketed NMDA receptor antagonist NMDA receptor Anesthesia; Psychiatry (depression) Small molecule

Target snapshot

Ketamine load (Ketamine load) — University of Pennsylvania. Ketamine is an NMDA receptor antagonist that blocks glutamate signaling in the brain, producing rapid-onset anesthetic and dissociative effects.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Ketamine load TARGET	Ketamine load	University of Pennsylvania	marketed	NMDA receptor antagonist	NMDA receptor
Namenda	MEMANTINE	AbbVie	marketed	N-methyl-D-aspartate Receptor Antagonist	Glutamate NMDA receptor; GRIN1/GRIN2A	2003-01-01
Felbatol	FELBAMATE	Mylan Speciality Lp	marketed	Anti-epileptic Agent [EPC]	NMDA receptor-ionophore complex	1993-01-01
QUINIDINE	QUINIDINE		marketed		sigma-1 receptor, NMDA receptor, CYP2D6	1950-01-01
Methadone Hydrochloride	METHADONE	Specgx Llc	marketed	Opioid Agonist	mu-opioid receptors, NMDA receptor	1947-01-01
Nitrous Oxide/Oxygen	Nitrous Oxide/Oxygen	Nationwide Children's Hospital	marketed	Inhalational anesthetic and analgesic gas	NMDA receptor antagonist; GABAergic potentiator
Oxygen/nitrous oxide equimolar mix	Oxygen/nitrous oxide equimolar mix	Hospital St. Joseph, Marseille, France	marketed	Inhalational anesthetic/analgesic gas mixture	NMDA receptor antagonist; endogenous opioid system modulation

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (NMDA receptor antagonist class)

1. Turku University Hospital · 3 drugs in this class
2. H. Lundbeck A/S · 2 drugs in this class
3. Ciusss de L'Est de l'Île de Montréal · 2 drugs in this class
4. Shalvata Mental Health Center · 2 drugs in this class
5. New York State Psychiatric Institute · 2 drugs in this class
6. Auris Medical AG · 1 drug in this class
7. AstraZeneca · 1 drug in this class
8. Alameda Health System · 1 drug in this class
9. Centre Hospitalier Universitaire de Nice · 1 drug in this class
10. Asker & Baerum Hospital · 1 drug in this class