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K-924 LD — Competitive Intelligence Brief
phase 3
Dopamine D2/D3 receptor agonist
Dopamine D2 receptor, Dopamine D3 receptor
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
K-924 LD (K-924 LD) — Kowa Company, Ltd.. K-924 LD is a long-acting dopamine D2/D3 receptor agonist designed to provide sustained dopaminergic activity for extended treatment intervals.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| K-924 LD TARGET | K-924 LD | Kowa Company, Ltd. | phase 3 | Dopamine D2/D3 receptor agonist | Dopamine D2 receptor, Dopamine D3 receptor | |
| ropinirole CR-RLS | ropinirole CR-RLS | GlaxoSmithKline | marketed | Dopamine D2/D3 receptor agonist | Dopamine D2 receptor, Dopamine D3 receptor | |
| IM aripiprazole once monthly | IM aripiprazole once monthly | University of Utah | marketed | Atypical antipsychotic | Dopamine D2 receptor, Dopamine D3 receptor | |
| Ropinirole (Requip) | Ropinirole (Requip) | St. Luke's-Roosevelt Hospital Center | marketed | Dopamine D2/D3 receptor agonist | Dopamine D2 receptor, Dopamine D3 receptor | |
| aripiprazole long acting injectable formulation | aripiprazole long acting injectable formulation | Vanguard Research Group | marketed | Atypical antipsychotic (dopamine partial agonist) | Dopamine D2 receptor, Dopamine D3 receptor | |
| Raclopride C11 | Raclopride C11 | University of North Carolina, Chapel Hill | marketed | Dopamine D2/D3 receptor antagonist (PET imaging agent) | Dopamine D2 receptor, Dopamine D3 receptor | |
| [11C]raclopride | [11C]raclopride | New York State Psychiatric Institute | marketed | Dopamine D2/D3 receptor antagonist (PET imaging agent) | Dopamine D2 receptor, Dopamine D3 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Dopamine D2/D3 receptor agonist class)
- GlaxoSmithKline · 1 drug in this class
- Kowa Company, Ltd. · 1 drug in this class
- Pharma Two B Ltd. · 1 drug in this class
- St. Luke's-Roosevelt Hospital Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). K-924 LD — Competitive Intelligence Brief. https://druglandscape.com/ci/k-924-ld. Accessed 2026-06-10.
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