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Isoniazid (H) — Competitive Intelligence Brief
phase 3
Nicotinamide analog; first-line antituberculous agent
Enoyl-ACP reductase (InhA); catalase-peroxidase (KatG)
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Isoniazid (H) (Isoniazid (H)) — University College, London. Isoniazid inhibits mycobacterial cell wall synthesis by blocking mycolic acid production, which is essential for Mycobacterium tuberculosis survival.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Isoniazid (H) TARGET | Isoniazid (H) | University College, London | phase 3 | Nicotinamide analog; first-line antituberculous agent | Enoyl-ACP reductase (InhA); catalase-peroxidase (KatG) | |
| Pyrazinamide (Z) | Pyrazinamide (Z) | Global Alliance for TB Drug Development | phase 3 | Nicotinamide analog; antituberculous agent | Pantothenate synthetase (PanC); pyrazinamidase activation |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nicotinamide analog; first-line antituberculous agent class)
- University College, London · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Isoniazid (H) — Competitive Intelligence Brief. https://druglandscape.com/ci/isoniazid-h. Accessed 2026-06-10.
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