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Irinotecan/Cetuximab — Competitive Intelligence Brief

Irinotecan/Cetuximab (Irinotecan/Cetuximab) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy and monoclonal antibody. Area: Oncology.

phase 3 Combination chemotherapy and monoclonal antibody Topoisomerase I (irinotecan); EGFR (cetuximab) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Irinotecan/Cetuximab (Irinotecan/Cetuximab) — Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente. Irinotecan inhibits topoisomerase I to damage cancer cell DNA, while cetuximab blocks EGFR signaling to prevent tumor growth and enhance chemotherapy sensitivity.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Irinotecan/Cetuximab TARGET Irinotecan/Cetuximab Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente phase 3 Combination chemotherapy and monoclonal antibody Topoisomerase I (irinotecan); EGFR (cetuximab)
FluCAM [Fludara + Campath] FluCAM [Fludara + Campath] Genzyme, a Sanofi Company phase 3 Combination chemotherapy and monoclonal antibody Ribonucleotide reductase / DNA polymerase (fludarabine); CD52 (alemtuzumab)
Chemotherapy and antibodies Chemotherapy and antibodies St. Jude Children's Research Hospital phase 3 Combination chemotherapy and monoclonal antibody therapy

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy and monoclonal antibody class)

  1. Genzyme, a Sanofi Company · 1 drug in this class
  2. Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Irinotecan/Cetuximab — Competitive Intelligence Brief. https://druglandscape.com/ci/irinotecan-cetuximab. Accessed 2026-05-17.

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