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Ipilimumab infusion — Competitive Intelligence Brief

Ipilimumab infusion (Ipilimumab infusion) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CTLA-4 inhibitor. Area: Oncology.

phase 3 CTLA-4 inhibitor CTLA-4 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Ipilimumab infusion (Ipilimumab infusion) — The Netherlands Cancer Institute. Ipilimumab blocks CTLA-4 on T cells, removing an inhibitory signal and enhancing anti-tumor immune responses.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Ipilimumab infusion TARGET Ipilimumab infusion The Netherlands Cancer Institute phase 3 CTLA-4 inhibitor CTLA-4
Imjudo TREMELIMUMAB AstraZeneca marketed CTLA-4-directed Blocking Antibody [EPC] CTLA-4 2022-01-01
Nivolumab in combination with Ipilimumab Nivolumab in combination with Ipilimumab Bristol-Myers Squibb marketed Checkpoint inhibitor combination (PD-1 inhibitor + CTLA-4 inhibitor) PD-1 and CTLA-4
tremelimumab (treme) tremelimumab (treme) AstraZeneca marketed CTLA-4 inhibitor CTLA-4
Ivonescimab, docetaxel Ivonescimab, docetaxel Akeso phase 3 PD-L1/CTLA-4 bispecific antibody + taxane chemotherapy PD-L1, CTLA-4 (ivonescimab); β-tubulin (docetaxel)
Fotemustine and Ipilimumab Fotemustine and Ipilimumab Italian Network for Tumor Biotherapy Foundation phase 3 Chemotherapy + immune checkpoint inhibitor combination DNA alkylation (fotemustine); CTLA-4 (ipilimumab)
IBI310&Sintilimab IBI310&Sintilimab Innovent Biologics (Suzhou) Co. Ltd. phase 3 Bispecific antibody (IBI310) + PD-1 inhibitor (Sintilimab) CTLA-4, TIM-3 (IBI310); PD-1 (Sintilimab)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CTLA-4 inhibitor class)

  1. AstraZeneca · 3 drugs in this class
  2. Federation Francophone de Cancerologie Digestive · 1 drug in this class
  3. Providence Health & Services · 1 drug in this class
  4. Shanghai Henlius Biotech · 1 drug in this class
  5. TSH Biopharm Corporation Limited · 1 drug in this class
  6. Takara Bio Inc. · 1 drug in this class
  7. The Netherlands Cancer Institute · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ipilimumab infusion — Competitive Intelligence Brief. https://druglandscape.com/ci/ipilimumab-infusion. Accessed 2026-05-14.

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