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Intranasal dexmedetomidine-esketamine — Competitive Intelligence Brief
marketed
Alpha-2 adrenergic agonist / NMDA receptor antagonist combination
Alpha-2 adrenergic receptors; NMDA receptor
Anesthesia / Sedation / Acute Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Intranasal dexmedetomidine-esketamine (Intranasal dexmedetomidine-esketamine) — Peking University First Hospital. This combination drug acts as an alpha-2 adrenergic agonist (dexmedetomidine) and an NMDA receptor antagonist (esketamine) delivered intranasally to produce rapid sedation and analgesia.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Intranasal dexmedetomidine-esketamine TARGET | Intranasal dexmedetomidine-esketamine | Peking University First Hospital | marketed | Alpha-2 adrenergic agonist / NMDA receptor antagonist combination | Alpha-2 adrenergic receptors; NMDA receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Alpha-2 adrenergic agonist / NMDA receptor antagonist combination class)
- Peking University First Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Intranasal dexmedetomidine-esketamine — Competitive Intelligence Brief. https://druglandscape.com/ci/intranasal-dexmedetomidine-esketamine. Accessed 2026-05-17.
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