Last reviewed · How we verify
intramuscular paraldehyde — Competitive Intelligence Brief
phase 3
Barbiturate
GABA transaminase
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
intramuscular paraldehyde (intramuscular paraldehyde) — Kamuzu University of Health Sciences. Paraldehyde is a sedative and anticonvulsant that acts by inhibiting the activity of GABA transaminase, leading to increased levels of GABA in the brain.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| intramuscular paraldehyde TARGET | intramuscular paraldehyde | Kamuzu University of Health Sciences | phase 3 | Barbiturate | GABA transaminase | |
| Sabril® | Sabril® | Lundbeck LLC | marketed | GABA transaminase inhibitor | GABA transaminase (ABAT) | |
| Butalbital, Aspirin And Caffeine | BUTALBITAL | Actavis Labs Ut Inc | marketed | Barbiturate [EPC] | GABA-A receptor alpha-1/beta-3/gamma-2 | 1976-01-01 |
| Brevital Sodium | METHOHEXITAL | Ph Health | marketed | Barbiturate | GABA-A receptor alpha-1/beta-3/gamma-2 | 1960-01-01 |
| pentothal sodium | pentothal sodium | Ajou University School of Medicine | marketed | Barbiturate | GABA-A receptor | |
| Phenobarbital Sodium Injection | Phenobarbital Sodium Injection | PharPoint Research, Inc. | marketed | Barbiturate | GABA-A receptor | |
| Etomidate Injection | Etomidate Injection | Korea University Anam Hospital | marketed | Non-barbiturate hypnotic; GABA-A receptor positive allosteric modulator | GABA-A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Barbiturate class)
- Ajou University School of Medicine · 1 drug in this class
- Kamuzu University of Health Sciences · 1 drug in this class
- Ph Health · 1 drug in this class
- PharPoint Research, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). intramuscular paraldehyde — Competitive Intelligence Brief. https://druglandscape.com/ci/intramuscular-paraldehyde. Accessed 2026-06-10.
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