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Inhaled Loxapine — Competitive Intelligence Brief

Inhaled Loxapine (Inhaled Loxapine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Atypical antipsychotic. Area: Psychiatry.

phase 3 Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor Psychiatry Small molecule Live · refreshed every 30 min

Target snapshot

Inhaled Loxapine (Inhaled Loxapine) — Alexza Pharmaceuticals, Inc.. Inhaled loxapine is a rapid-acting antipsychotic that blocks dopamine and serotonin receptors in the brain to reduce acute agitation.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Inhaled Loxapine TARGET Inhaled Loxapine Alexza Pharmaceuticals, Inc. phase 3 Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor
Quetiapine (drug) Quetiapine (drug) Medical University of Vienna marketed Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor
Lithium carbonate + perospirone hydrochloride Lithium carbonate + perospirone hydrochloride Shanghai Mental Health Center marketed Mood stabilizer + atypical antipsychotic combination Inositol monophosphatase, GSK-3 (lithium); dopamine D2 receptor, serotonin 5-HT2A receptor (perospirone)
Fluoxetine+Olanzapine Fluoxetine+Olanzapine University Health Network, Toronto marketed SSRI + atypical antipsychotic combination Serotonin transporter (SERT), dopamine D2 receptor, serotonin 5-HT2A receptor
Quetiapine Fumarate Sustained Release Quetiapine Fumarate Sustained Release AstraZeneca marketed Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor
Olanzapine-Fluoxetine Combination Olanzapine-Fluoxetine Combination All India Institute of Medical Sciences, Bhubaneswar marketed Atypical antipsychotic + SSRI combination Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT)
Risperidone and Ramelteon Risperidone and Ramelteon All India Institute of Medical Sciences, Bhubaneswar marketed Atypical antipsychotic + melatonin receptor agonist combination Dopamine D2 receptor, serotonin 5-HT2A receptor, melatonin MT1/MT2 receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Atypical antipsychotic class)

  1. Shanghai Mental Health Center · 10 drugs in this class
  2. AstraZeneca · 6 drugs in this class
  3. Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
  4. Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
  5. Eli Lilly and Company · 4 drugs in this class
  6. Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
  7. Medical University of Vienna · 2 drugs in this class
  8. Organon and Co · 2 drugs in this class
  9. Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
  10. H. Lundbeck A/S · 2 drugs in this class

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Cite this brief

Drug Landscape (2026). Inhaled Loxapine — Competitive Intelligence Brief. https://druglandscape.com/ci/inhaled-loxapine. Accessed 2026-05-16.

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