Who are Ingenol Mebutate (Picato®)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): ingenol mebutate 0.015%, Ingenol Mebutate (Reference), Ingenol Mebutate (Perrigo), Etavopivat tablets, PEP005 (ingenol mebutate) Gel, Ingenol metabute.

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Last reviewed 2026-05-16 · How we verify

Ingenol Mebutate (Picato®) — Competitive Intelligence Brief

Ingenol Mebutate (Picato®) (Ingenol Mebutate (Picato®)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Protein kinase C (PKC) activator. Area: Dermatology.

phase 3 Protein kinase C (PKC) activator Protein kinase C (PKC) Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Ingenol Mebutate (Picato®) (Ingenol Mebutate (Picato®)) — Actavis Inc.. Ingenol mebutate is a protein kinase C (PKC) activator that induces rapid necrosis of actinic keratosis cells and promotes immune-mediated clearance of treated lesions.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Ingenol Mebutate (Picato®) TARGET	Ingenol Mebutate (Picato®)	Actavis Inc.	phase 3	Protein kinase C (PKC) activator	Protein kinase C (PKC)
ingenol mebutate 0.015%	ingenol mebutate 0.015%	Icahn School of Medicine at Mount Sinai	marketed	Protein kinase C (PKC) activator	Protein kinase C (PKC)
Ingenol Mebutate (Reference)	Ingenol Mebutate (Reference)	Padagis LLC	phase 3	Protein kinase C (PKC) activator	Protein kinase C (PKC)
Ingenol Mebutate (Perrigo)	Ingenol Mebutate (Perrigo)	Padagis LLC	phase 3	Protein kinase C (PKC) activator	Protein kinase C (PKC)
Etavopivat tablets	Etavopivat tablets	Forma Therapeutics, Inc.	phase 3	Protein kinase C (PKC) activator	PKC (Protein Kinase C)
PEP005 (ingenol mebutate) Gel	PEP005 (ingenol mebutate) Gel	Peplin	phase 3	Protein kinase C (PKC) activator	Protein kinase C (PKC)
Ingenol metabute	Ingenol metabute	LEO Pharma	phase 3	Protein kinase C (PKC) activator	Protein kinase C (PKC)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Protein kinase C (PKC) activator class)

Padagis LLC · 2 drugs in this class
Actavis Inc. · 1 drug in this class
Forma Therapeutics, Inc. · 1 drug in this class
Icahn School of Medicine at Mount Sinai · 1 drug in this class
LEO Pharma · 1 drug in this class
Peplin · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ingenol Mebutate (Picato®) — Competitive Intelligence Brief. https://druglandscape.com/ci/ingenol-mebutate-picato. Accessed 2026-05-16.

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