Who are Ingenol mebutate gel 0.05 %'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): ingenol mebutate 0.05% gel, Inggenol Mebutate 0.015%, Generic Ingenol Mebutate.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-17 · How we verify

Ingenol mebutate gel 0.05 % — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Ingenol mebutate gel 0.05 % (Ingenol mebutate gel 0.05 %) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Protein kinase C activator. Area: Dermatology.

phase 3 Protein kinase C activator Protein kinase C (PKC) Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Ingenol mebutate gel 0.05 % (Ingenol mebutate gel 0.05 %) — LEO Pharma. Ingenol mebutate activates protein kinase C (PKC) to induce rapid necrosis of actinic keratosis cells and promote immune-mediated clearance of damaged skin.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Ingenol mebutate gel 0.05 % TARGET	Ingenol mebutate gel 0.05 %	LEO Pharma	phase 3	Protein kinase C activator	Protein kinase C (PKC)
ingenol mebutate 0.05% gel	ingenol mebutate 0.05% gel	Neal D. Bhatia, MD	marketed	Protein kinase C activator	Protein kinase C (PKC)
Inggenol Mebutate 0.015%	Inggenol Mebutate 0.015%	Goldman, Butterwick, Fitzpatrick and Groff	marketed	Protein kinase C activator	Protein kinase C (PKC)
Generic Ingenol Mebutate	Generic Ingenol Mebutate	Actavis Inc.	phase 3	Protein kinase C activator	Protein kinase C (PKC)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Protein kinase C activator class)

Actavis Inc. · 1 drug in this class
Goldman, Butterwick, Fitzpatrick and Groff · 1 drug in this class
LEO Pharma · 1 drug in this class
Neal D. Bhatia, MD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Ingenol mebutate gel 0.05 % — Competitive Intelligence Brief. https://druglandscape.com/ci/ingenol-mebutate-gel-0-05. Accessed 2026-05-17.

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