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Infusional 5-FU/LV with Irinotecan — Competitive Intelligence Brief
phase 3
Chemotherapy combination (antimetabolite + topoisomerase I inhibitor)
Thymidylate synthase (5-FU); Topoisomerase I (Irinotecan)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Infusional 5-FU/LV with Irinotecan (Infusional 5-FU/LV with Irinotecan) — Pfizer. This combination chemotherapy regimen inhibits DNA synthesis and topoisomerase I to kill rapidly dividing cancer cells.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Infusional 5-FU/LV with Irinotecan TARGET | Infusional 5-FU/LV with Irinotecan | Pfizer | phase 3 | Chemotherapy combination (antimetabolite + topoisomerase I inhibitor) | Thymidylate synthase (5-FU); Topoisomerase I (Irinotecan) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Chemotherapy combination (antimetabolite + topoisomerase I inhibitor) class)
- Pfizer · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Infusional 5-FU/LV with Irinotecan — Competitive Intelligence Brief. https://druglandscape.com/ci/infusional-5-fu-lv-with-irinotecan. Accessed 2026-05-18.
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