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induction chemotherapy (mDCF) — Competitive Intelligence Brief

induction chemotherapy (mDCF) (induction chemotherapy (mDCF)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy regimen. Area: Oncology.

phase 3 Combination chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

induction chemotherapy (mDCF) (induction chemotherapy (mDCF)) — Federation Francophone de Cancerologie Digestive. mDCF is a combination chemotherapy regimen that uses docetaxel, cisplatin, and fluorouracil to inhibit cancer cell division and induce apoptosis in gastric and esophageal cancers.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
induction chemotherapy (mDCF) TARGET induction chemotherapy (mDCF) Federation Francophone de Cancerologie Digestive phase 3 Combination chemotherapy regimen
Dexamethasona, Idarubicine, ARA-C, Methotrexate Dexamethasona, Idarubicine, ARA-C, Methotrexate PETHEMA Foundation marketed Combination chemotherapy regimen
Carboplatin, Etoposide, Ifosfamide Carboplatin, Etoposide, Ifosfamide University Hospital Muenster marketed Combination chemotherapy regimen DNA (multiple mechanisms: alkylation, cross-linking, topoisomerase II inhibition)
FEC FEC Hoffmann-La Roche marketed Combination chemotherapy regimen
Consolidation Chemotherapy Consolidation Chemotherapy National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos marketed Combination chemotherapy regimen
chemotherapy of mFOLFOX6 or FOLFIRI chemotherapy of mFOLFOX6 or FOLFIRI Xu jianmin marketed Combination chemotherapy regimen Thymidylate synthase (5-FU), DNA topoisomerase I (irinotecan), DNA (oxaliplatin)
CVP CVP SCRI Development Innovations, LLC marketed Combination chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy regimen class)

  1. Sun Yat-sen University · 5 drugs in this class
  2. Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
  3. Hoffmann-La Roche · 2 drugs in this class
  4. University Hospital, Bordeaux · 2 drugs in this class
  5. Beijing Friendship Hospital · 1 drug in this class
  6. Centre Hospitalier Universitaire Dijon · 1 drug in this class
  7. Amgen · 1 drug in this class
  8. Chungnam National University Hospital · 1 drug in this class
  9. AstraZeneca · 1 drug in this class
  10. Children's Cancer Group, China · 1 drug in this class

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Cite this brief

Drug Landscape (2026). induction chemotherapy (mDCF) — Competitive Intelligence Brief. https://druglandscape.com/ci/induction-chemotherapy-mdcf. Accessed 2026-06-10.

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