Who are Imiquimod 3.75% Cream's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Imiquimod 5% Cream, Aldara (imiquimod) cream, 5%, Imiquimod 5% cream with prior curettage, Aldara (Imiquimod), IV Tulisokibart, Topical Imiquimod.

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Last reviewed 2026-05-16 · How we verify

Imiquimod 3.75% Cream — Competitive Intelligence Brief

Imiquimod 3.75% Cream (Imiquimod 3.75% Cream) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: TLR7 agonist. Area: Dermatology/Oncology.

marketed TLR7 agonist TLR7 (Toll-like receptor 7) Dermatology/Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Imiquimod 3.75% Cream (Imiquimod 3.75% Cream) — Medical University of Graz. Imiquimod is a toll-like receptor 7 (TLR7) agonist that activates innate immune responses to treat skin lesions.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Imiquimod 3.75% Cream TARGET	Imiquimod 3.75% Cream	Medical University of Graz	marketed	TLR7 agonist	TLR7 (Toll-like receptor 7)
Imiquimod 5% Cream	Imiquimod 5% Cream	Massachusetts General Hospital	marketed	TLR7 agonist / Immune response modifier	TLR7 (Toll-like receptor 7)
Aldara (imiquimod) cream, 5%	Aldara (imiquimod) cream, 5%	Graceway Pharmaceuticals, LLC	marketed	TLR7 agonist	TLR7 (Toll-like receptor 7)
Imiquimod 5% cream with prior curettage	Imiquimod 5% cream with prior curettage	Maastricht University Medical Center	phase 3	TLR7 agonist / Immune response modifier	TLR7 (Toll-like receptor 7)
Aldara (Imiquimod)	Aldara (Imiquimod)	MEDA Pharma GmbH & Co. KG	phase 3	TLR7 agonist	TLR7 (Toll-like receptor 7)
IV Tulisokibart	IV Tulisokibart	Merck Sharp & Dohme LLC	phase 3	TLR7 agonist	TLR7
Topical Imiquimod	Topical Imiquimod	Medical University of Vienna	phase 3	TLR7 agonist	TLR7 (Toll-like receptor 7)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (TLR7 agonist class)

Apotex Inc. · 1 drug in this class
Elion Therapeutics, Inc. · 1 drug in this class
Graceway Pharmaceuticals, LLC · 1 drug in this class
MEDA Pharma GmbH & Co. KG · 1 drug in this class
Medical University of Graz · 1 drug in this class
Medical University of Vienna · 1 drug in this class
Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Imiquimod 3.75% Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/imiquimod-3-75-cream. Accessed 2026-05-16.

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