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Imatinib mesylate (STI571) — Competitive Intelligence Brief
phase 3
Tyrosine kinase inhibitor
BCR-ABL, PDGF receptor, c-KIT
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Imatinib mesylate (STI571) (Imatinib mesylate (STI571)) — M.D. Anderson Cancer Center. Imatinib is a tyrosine kinase inhibitor that blocks the BCR-ABL fusion protein and other kinases, preventing abnormal cell proliferation in chronic myeloid leukemia and other cancers.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Imatinib mesylate (STI571) TARGET | Imatinib mesylate (STI571) | M.D. Anderson Cancer Center | phase 3 | Tyrosine kinase inhibitor | BCR-ABL, PDGF receptor, c-KIT | |
| Inlyta | Axitinib | Pfizer | marketed | Receptor tyrosine kinase inhibitor | Vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2, VEGFR-3 | 2012-01-01 |
| Vizimpro | Dacomitinib | Pfizer Inc. | marketed | Tyrosine kinase inhibitor (TKI); Pan-HER inhibitor | Cyclin-G-associated kinase, Receptor-interacting serine/threonine-protein kinase 2, Receptor-interacting serine/threonine-protein kinase 3 | |
| Sunitinib Malate (SU011248) | Sunitinib Malate (SU011248) | H. Lee Moffitt Cancer Center and Research Institute | marketed | Multi-targeted tyrosine kinase inhibitor | VEGFR, PDGFR, KIT, FLT3 | |
| Osimertinib (Osi) | Osimertinib (Osi) | AbbVie | marketed | EGFR tyrosine kinase inhibitor (third-generation) | EGFR (Epidermal Growth Factor Receptor) | |
| imatinib (IM) | imatinib (IM) | First Affiliated Hospital, Sun Yat-Sen University | marketed | Tyrosine kinase inhibitor | BCR-ABL, KIT, PDGFRA | |
| DW6012(Dasidiem tab. 10/100mg) | DW6012(Dasidiem tab. 10/100mg) | Dong Wha Pharmaceutical Co. Ltd. | marketed | Tyrosine kinase inhibitor combination | BCR-ABL, SRC family kinases |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Tyrosine kinase inhibitor class)
- Jiangsu HengRui Medicine Co., Ltd. · 5 drugs in this class
- Centre Leon Berard · 2 drugs in this class
- AB Science · 2 drugs in this class
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- Betta Pharmaceuticals Co., Ltd. · 1 drug in this class
- Angion Biomedica Corp · 1 drug in this class
- Beijing InnoCare Pharma Tech Co., Ltd. · 1 drug in this class
- Chang-Ming Huang, Prof. · 1 drug in this class
- Deciphera Pharmaceuticals, LLC · 1 drug in this class
- AstraZeneca · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Imatinib mesylate (STI571) — Competitive Intelligence Brief. https://druglandscape.com/ci/imatinib-mesylate-sti571. Accessed 2026-05-16.
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