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ICI35,868 (Diprivan) — Competitive Intelligence Brief

ICI35,868 (Diprivan) (ICI35,868 (Diprivan)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Intravenous sedative-hypnotic. Area: Anesthesia.

phase 3 Intravenous sedative-hypnotic GABA-A receptor Anesthesia Small molecule Live · refreshed every 30 min

Target snapshot

ICI35,868 (Diprivan) (ICI35,868 (Diprivan)) — AstraZeneca. Propofol is a rapid-acting intravenous sedative-hypnotic agent that enhances inhibitory GABAergic neurotransmission in the central nervous system.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
ICI35,868 (Diprivan) TARGET ICI35,868 (Diprivan) AstraZeneca phase 3 Intravenous sedative-hypnotic GABA-A receptor
Zulresso BREXANOLONE Sage Therap marketed Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator GABA-A receptor alpha-1/beta-2/gamma-2 2019-01-01
Onfi CLOBAZAM Lundbeck Pharms Llc marketed Benzodiazepine [EPC] GABA-A receptor alpha-1/beta-2/gamma-2 2011-01-01
Lusedra FOSPROPOFOL marketed fospropofol GABA-A receptor 2008-01-01
Campral ACAMPROSATE Allergan/AbbVie marketed acamprosate GABA-A receptor alpha-1/beta-3/gamma-2 2004-01-01
Sonata ZALEPLON Pfizer marketed gamma-Aminobutyric Acid A Receptor Agonist [EPC] GABA-A receptor alpha-1/beta-2/gamma-2 1999-01-01
Suprane DESFLURANE Baxter marketed General Anesthetic [EPC] GABA-A receptor; anion channel 1992-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Intravenous sedative-hypnotic class)

  1. AstraZeneca · 1 drug in this class
  2. Brugmann University Hospital · 1 drug in this class
  3. Centre Hospitalier Universitaire Dijon · 1 drug in this class
  4. Fayoum University Hospital · 1 drug in this class
  5. Iuliu Hatieganu University of Medicine and Pharmacy · 1 drug in this class
  6. RenJi Hospital · 1 drug in this class
  7. Second Affiliated Hospital, School of Medicine, Zhejiang University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ICI35,868 (Diprivan) — Competitive Intelligence Brief. https://druglandscape.com/ci/ici35-868-diprivan. Accessed 2026-05-16.

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