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I131 — Competitive Intelligence Brief
phase 3
Radiopharmaceutical
Sodium-iodide symporter (NIS)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
I131 (I131) — Gustave Roussy, Cancer Campus, Grand Paris. Iodine-131 is a radioactive isotope that emits beta particles to destroy thyroid cancer cells and other iodine-avid malignancies.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| I131 TARGET | I131 | Gustave Roussy, Cancer Campus, Grand Paris | phase 3 | Radiopharmaceutical | Sodium-iodide symporter (NIS) | |
| Fludeoxyglucose F 18 (FDG) | Fludeoxyglucose F 18 (FDG) | Teva Branded Pharmaceutical Products R&D, Inc. | marketed | Radiopharmaceutical; PET imaging agent | Glucose transporter (GLUT1); hexokinase | |
| Radium-223 | radium-223 | Pfizer | marketed | Radiopharmaceutical | Bone cells | |
| [Ga-68]PSMA | [Ga-68]PSMA | Norbert Avril, M.D. | marketed | PET imaging agent / radiopharmaceutical | PSMA (prostate-specific membrane antigen) | |
| Rubidium-82 | Rubidium-82 | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | marketed | PET radiopharmaceutical | Na+/K+-ATPase pump (myocardial uptake mechanism) | |
| Sr-89 | Sr-89 | Peking Union Medical College Hospital | marketed | Radiopharmaceutical; beta-emitting radioisotope | Bone hydroxyapatite (calcium analog); osteoblasts in areas of increased bone metabolism | |
| Tc 99m filtered sulfur colloid | Tc 99m filtered sulfur colloid | Memorial Health University Medical Center | marketed | Radiopharmaceutical diagnostic agent |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Radiopharmaceutical class)
- Amsterdam UMC, location VUmc · 1 drug in this class
- Blue Earth Diagnostics · 1 drug in this class
- Brigham and Women's Hospital · 1 drug in this class
- Genzyme, a Sanofi Company · 1 drug in this class
- Gustave Roussy, Cancer Campus, Grand Paris · 1 drug in this class
- HTA Co., Ltd. · 1 drug in this class
- IRCCS San Raffaele · 1 drug in this class
- ITEL Telecomunicazioni Srl · 1 drug in this class
- M.D. Anderson Cancer Center · 1 drug in this class
- Michael C Roarke, MD · 1 drug in this class
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Cite this brief
Drug Landscape (2026). I131 — Competitive Intelligence Brief. https://druglandscape.com/ci/i131. Accessed 2026-05-14.
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