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I-DXd — Competitive Intelligence Brief

I-DXd (I-DXd) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CD22-targeting antibody-drug conjugate. Area: Oncology.

phase 2 CD22-targeting antibody-drug conjugate CD22 Oncology Biologic Live · refreshed every 30 min

Target snapshot

I-DXd (I-DXd) — Merck Sharp & Dohme LLC. Targeting CD22 with antibody-drug conjugate

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
I-DXd TARGET I-DXd Merck Sharp & Dohme LLC phase 2 CD22-targeting antibody-drug conjugate CD22
Lumoxiti MOXETUMOMAB PASUDOTOX AstraZeneca marketed B-cell receptor CD22 2018-01-01
INOTUZUMAB OZOGAMICIN INOTUZUMAB OZOGAMICIN marketed CD22-directed Immunoconjugate [EPC] CD22 2017-01-01
Besponsa inotuzumab-ozogamicin Pfizer marketed Antibody-drug conjugate (ADC) CD22 2017-01-01
Besponsa inotuzumab Pfizer marketed CD22-directed Immunoconjugate [EPC] CD22 2017-01-01
Inotuzumab ozogamicin-dose level 1 Inotuzumab ozogamicin-dose level 1 Pfizer marketed Antibody-drug conjugate (ADC) CD22
Besponsa Inotuzumab Ozogamicin Pfizer Inc. marketed Antibody-drug conjugate (ADC) CD22

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CD22-targeting antibody-drug conjugate class)

  1. Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). I-DXd — Competitive Intelligence Brief. https://druglandscape.com/ci/i-dxd. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing