Last reviewed · How we verify
HZT-501 — Competitive Intelligence Brief
phase 3
Bispecific antibody
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
HZT-501 (HZT-501) — Amgen. HZT-501 is a bispecific antibody that simultaneously engages two distinct immune pathways to enhance anti-tumor T-cell responses.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| HZT-501 TARGET | HZT-501 | Amgen | phase 3 | Bispecific antibody | ||
| Elrexfio | Elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrexfio | elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrantamab | elrantamab | Pfizer | marketed | Bispecific Antibody | BCMA (B-cell maturation antigen) | |
| BAT2206 | BAT2206 | Bio-Thera Solutions | phase 3 | Bispecific antibody; dual checkpoint inhibitor | Likely PD-1 and LAG-3 (or similar dual checkpoint targets) | |
| Ivonescimab, docetaxel | Ivonescimab, docetaxel | Akeso | phase 3 | PD-L1/CTLA-4 bispecific antibody + taxane chemotherapy | PD-L1, CTLA-4 (ivonescimab); β-tubulin (docetaxel) | |
| IBI354 | IBI354 | Innovent Biologics (Suzhou) Co. Ltd. | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bispecific antibody class)
- Shanghai Miracogen Inc. · 3 drugs in this class
- Atom Therapeutics Co., Ltd · 2 drugs in this class
- Pfizer · 2 drugs in this class
- Allergan · 1 drug in this class
- AstraZeneca · 1 drug in this class
- BioNTech SE · 1 drug in this class
- DualityBio Inc. · 1 drug in this class
- Coherus Oncology, Inc. · 1 drug in this class
- Genmab · 1 drug in this class
- Amgen · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- HZT-501 CI watch — RSS
- HZT-501 CI watch — Atom
- HZT-501 CI watch — JSON
- HZT-501 alone — RSS
- Whole Bispecific antibody class — RSS
Cite this brief
Drug Landscape (2026). HZT-501 — Competitive Intelligence Brief. https://druglandscape.com/ci/hzt-501. Accessed 2026-06-10.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing