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HZT-501 — Competitive Intelligence Brief

HZT-501 (HZT-501) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific antibody. Area: Oncology.

phase 3 Bispecific antibody Oncology Small molecule Live · refreshed every 30 min

Target snapshot

HZT-501 (HZT-501) — Amgen. HZT-501 is a bispecific antibody that simultaneously engages two distinct immune pathways to enhance anti-tumor T-cell responses.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
HZT-501 TARGET HZT-501 Amgen phase 3 Bispecific antibody
Elrexfio Elranatamab Pfizer marketed Bispecific antibody BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells 2023-01-01
Elrexfio elranatamab Pfizer marketed Bispecific antibody BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells 2023-01-01
Elrantamab elrantamab Pfizer marketed Bispecific Antibody BCMA (B-cell maturation antigen)
BAT2206 BAT2206 Bio-Thera Solutions phase 3 Bispecific antibody; dual checkpoint inhibitor Likely PD-1 and LAG-3 (or similar dual checkpoint targets)
Ivonescimab, docetaxel Ivonescimab, docetaxel Akeso phase 3 PD-L1/CTLA-4 bispecific antibody + taxane chemotherapy PD-L1, CTLA-4 (ivonescimab); β-tubulin (docetaxel)
IBI354 IBI354 Innovent Biologics (Suzhou) Co. Ltd. phase 3 Bispecific antibody; PD-1/TGF-β inhibitor PD-1 and TGF-β

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bispecific antibody class)

  1. Shanghai Miracogen Inc. · 3 drugs in this class
  2. Atom Therapeutics Co., Ltd · 2 drugs in this class
  3. Pfizer · 2 drugs in this class
  4. Allergan · 1 drug in this class
  5. AstraZeneca · 1 drug in this class
  6. BioNTech SE · 1 drug in this class
  7. DualityBio Inc. · 1 drug in this class
  8. Coherus Oncology, Inc. · 1 drug in this class
  9. Genmab · 1 drug in this class
  10. Amgen · 1 drug in this class

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Cite this brief

Drug Landscape (2026). HZT-501 — Competitive Intelligence Brief. https://druglandscape.com/ci/hzt-501. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing