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Hyperbaric bupivacaine+Morphine — Competitive Intelligence Brief
marketed
Local anesthetic + opioid combination
Voltage-gated sodium channels (bupivacaine); mu opioid receptors (morphine)
Anesthesia / Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Hyperbaric bupivacaine+Morphine (Hyperbaric bupivacaine+Morphine) — Fundación Pública Andaluza Progreso y Salud. This combination uses bupivacaine (a local anesthetic) formulated as a hyperbaric solution with morphine (an opioid analgesic) to provide prolonged spinal anesthesia and analgesia.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Hyperbaric bupivacaine+Morphine TARGET | Hyperbaric bupivacaine+Morphine | Fundación Pública Andaluza Progreso y Salud | marketed | Local anesthetic + opioid combination | Voltage-gated sodium channels (bupivacaine); mu opioid receptors (morphine) | |
| Levobupivacaine plus sufentanil epidural infusion | Levobupivacaine plus sufentanil epidural infusion | University of Genova | marketed | Local anesthetic + opioid combination | Voltage-gated sodium channels (levobupivacaine); mu-opioid receptor (sufentanil) | |
| Bupivacaine + Sufentanil epidural | Bupivacaine + Sufentanil epidural | Charles University, Czech Republic | marketed | Local anesthetic + opioid combination | Voltage-gated sodium channels (bupivacaine); mu opioid receptor (sufentanil) | |
| Bupivacaine heavy and Morphine | Bupivacaine heavy and Morphine | Post Graduate Institute of Medical Education and Research, Chandigarh | marketed | Local anesthetic + opioid combination | Voltage-gated sodium channels (bupivacaine); mu-opioid receptor (morphine) | |
| Hyperbaric bupivacaine+Sufentanil | Hyperbaric bupivacaine+Sufentanil | Fundación Pública Andaluza Progreso y Salud | marketed | Local anesthetic + opioid combination | Voltage-gated sodium channels (bupivacaine); mu-opioid receptors (sufentanil) | |
| Levobupivacaine 0.07% + Sufentanil 0.3µg/ml | Levobupivacaine 0.07% + Sufentanil 0.3µg/ml | Dr Madeleine Wilwerth | phase 3 | Local anesthetic + opioid combination | Voltage-gated sodium channels (levobupivacaine); mu opioid receptor (sufentanil) | |
| Levobupivacaine 0.1% + Sufentanil 0.2µg/ml | Levobupivacaine 0.1% + Sufentanil 0.2µg/ml | Dr Madeleine Wilwerth | phase 3 | Local anesthetic + opioid combination | Voltage-gated sodium channels (levobupivacaine); mu opioid receptor (sufentanil) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Local anesthetic + opioid combination class)
- Dr Madeleine Wilwerth · 2 drugs in this class
- Fundación Pública Andaluza Progreso y Salud · 2 drugs in this class
- Charles University, Czech Republic · 1 drug in this class
- Post Graduate Institute of Medical Education and Research, Chandigarh · 1 drug in this class
- University of Genova · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Hyperbaric bupivacaine+Morphine — Competitive Intelligence Brief. https://druglandscape.com/ci/hyperbaric-bupivacaine-morphine. Accessed 2026-06-10.
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