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Hydroxychloroquine + lopinavir/ritonavir — Competitive Intelligence Brief
phase 3
Combination antiviral and immunomodulator
Viral protease (lopinavir/ritonavir); endosomal pH and autophagy pathways (hydroxychloroquine)
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
Hydroxychloroquine + lopinavir/ritonavir (Hydroxychloroquine + lopinavir/ritonavir) — UMC Utrecht. This combination uses hydroxychloroquine to modulate immune response and autophagy while lopinavir/ritonavir inhibits viral protease to reduce viral replication.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Hydroxychloroquine + lopinavir/ritonavir TARGET | Hydroxychloroquine + lopinavir/ritonavir | UMC Utrecht | phase 3 | Combination antiviral and immunomodulator | Viral protease (lopinavir/ritonavir); endosomal pH and autophagy pathways (hydroxychloroquine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination antiviral and immunomodulator class)
- UMC Utrecht · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Hydroxychloroquine + lopinavir/ritonavir — Competitive Intelligence Brief. https://druglandscape.com/ci/hydroxychloroquine-lopinavir-ritonavir. Accessed 2026-05-16.
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